K08 HL125807/HL/NHLBI NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2015	1
2016	2
2018	3
2019	2
2020	2
2021	3
2022	1
2025	0

1

Development of a Cardiac Sarcomere Functional Genomics Platform to Enable Scalable Interrogation of Human TNNT2 Variants.

Pettinato AM, Ladha FA, Mellert DJ, Legere N, Cohn R, Romano R, Thakar K, Chen YS, Hinson JT. Pettinato AM, et al. Circulation. 2020 Dec 8;142(23):2262-2275. doi: 10.1161/CIRCULATIONAHA.120.047999. Epub 2020 Oct 7. Circulation. 2020. PMID: 33025817 Free PMC article.

2

Single-Cell Resolution of Temporal Gene Expression during Heart Development.

DeLaughter DM, Bick AG, Wakimoto H, McKean D, Gorham JM, Kathiriya IS, Hinson JT, Homsy J, Gray J, Pu W, Bruneau BG, Seidman JG, Seidman CE. DeLaughter DM, et al. Dev Cell. 2016 Nov 21;39(4):480-490. doi: 10.1016/j.devcel.2016.10.001. Epub 2016 Nov 10. Dev Cell. 2016. PMID: 27840107 Free PMC article.

3

Sarcomere-Directed Calcium Reporters in Cardiomyocytes.

Campbell SG, Qyang Y, Hinson JT. Campbell SG, et al. Circ Res. 2019 Apr 12;124(8):1151-1153. doi: 10.1161/CIRCRESAHA.119.314877. Circ Res. 2019. PMID: 30973804 Free PMC article. No abstract available.

4

From GWAS Association to Function: Candidate Gene Screening Within Insulin Resistance-Associated Genomic Loci Using a Preadipocyte Differentiation Model.

Ladha FA, Stitzel ML, Hinson JT. Ladha FA, et al. Circ Res. 2020 Jan 31;126(3):347-349. doi: 10.1161/CIRCRESAHA.119.316405. Epub 2020 Jan 30. Circ Res. 2020. PMID: 31999535 Free PMC article. No abstract available.

5

Actinin BioID reveals sarcomere crosstalk with oxidative metabolism through interactions with IGF2BP2.

Ladha FA, Thakar K, Pettinato AM, Legere N, Ghahremani S, Cohn R, Romano R, Meredith E, Chen YS, Hinson JT. Ladha FA, et al. Cell Rep. 2021 Aug 10;36(6):109512. doi: 10.1016/j.celrep.2021.109512. Cell Rep. 2021. PMID: 34380038 Free PMC article.

6

Reading Frame Repair of TTN Truncation Variants Restores Titin Quantity and Functions.

Romano R, Ghahremani S, Zimmerman T, Legere N, Thakar K, Ladha FA, Pettinato AM, Hinson JT. Romano R, et al. Circulation. 2022 Jan 18;145(3):194-205. doi: 10.1161/CIRCULATIONAHA.120.049997. Epub 2021 Dec 14. Circulation. 2022. PMID: 34905694 Free PMC article.

7

A Contraction Stress Model of Hypertrophic Cardiomyopathy due to Sarcomere Mutations.

Cohn R, Thakar K, Lowe A, Ladha FA, Pettinato AM, Romano R, Meredith E, Chen YS, Atamanuk K, Huey BD, Hinson JT. Cohn R, et al. Stem Cell Reports. 2019 Jan 8;12(1):71-83. doi: 10.1016/j.stemcr.2018.11.015. Epub 2018 Dec 13. Stem Cell Reports. 2019. PMID: 30554920 Free PMC article.

8

Telomere shortening is a hallmark of genetic cardiomyopathies.

Chang ACY, Chang ACH, Kirillova A, Sasagawa K, Su W, Weber G, Lin J, Termglinchan V, Karakikes I, Seeger T, Dainis AM, Hinson JT, Seidman J, Seidman CE, Day JW, Ashley E, Wu JC, Blau HM. Chang ACY, et al. Proc Natl Acad Sci U S A. 2018 Sep 11;115(37):9276-9281. doi: 10.1073/pnas.1714538115. Epub 2018 Aug 27. Proc Natl Acad Sci U S A. 2018. PMID: 30150400 Free PMC article.

9

Force Generation via β-Cardiac Myosin, Titin, and α-Actinin Drives Cardiac Sarcomere Assembly from Cell-Matrix Adhesions.

Chopra A, Kutys ML, Zhang K, Polacheck WJ, Sheng CC, Luu RJ, Eyckmans J, Hinson JT, Seidman JG, Seidman CE, Chen CS. Chopra A, et al. Dev Cell. 2018 Jan 8;44(1):87-96.e5. doi: 10.1016/j.devcel.2017.12.012. Epub 2018 Jan 8. Dev Cell. 2018. PMID: 29316444 Free PMC article.

10

Sarcomere function activates a p53-dependent DNA damage response that promotes polyploidization and limits in vivo cell engraftment.

Pettinato AM, Yoo D, VanOudenhove J, Chen YS, Cohn R, Ladha FA, Yang X, Thakar K, Romano R, Legere N, Meredith E, Robson P, Regnier M, Cotney JL, Murry CE, Hinson JT. Pettinato AM, et al. Cell Rep. 2021 May 4;35(5):109088. doi: 10.1016/j.celrep.2021.109088. Cell Rep. 2021. PMID: 33951429 Free PMC article.

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