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Biophysical forces mediated by respiration maintain lung alveolar epithelial cell fate.
Shiraishi K, Shah PP, Morley MP, Loebel C, Santini GT, Katzen J, Basil MC, Lin SM, Planer JD, Cantu E, Jones DL, Nottingham AN, Li S, Cardenas-Diaz FL, Zhou S, Burdick JA, Jain R, Morrisey EE. Shiraishi K, et al. Cell. 2023 Mar 30;186(7):1478-1492.e15. doi: 10.1016/j.cell.2023.02.010. Epub 2023 Mar 3. Cell. 2023. PMID: 36870331 Free PMC article.
Single-cell transcriptomics reveals skewed cellular communication and phenotypic shift in pulmonary artery remodeling.
Crnkovic S, Valzano F, Fließer E, Gindlhuber J, Thekkekara Puthenparampil H, Basil M, Morley MP, Katzen J, Gschwandtner E, Klepetko W, Cantu E, Wolinski H, Olschewski H, Lindenmann J, Zhao YY, Morrisey EE, Marsh LM, Kwapiszewska G. Crnkovic S, et al. JCI Insight. 2022 Oct 24;7(20):e153471. doi: 10.1172/jci.insight.153471. JCI Insight. 2022. PMID: 36099047 Free PMC article.
Human distal airways contain a multipotent secretory cell that can regenerate alveoli.
Basil MC, Cardenas-Diaz FL, Kathiriya JJ, Morley MP, Carl J, Brumwell AN, Katzen J, Slovik KJ, Babu A, Zhou S, Kremp MM, McCauley KB, Li S, Planer JD, Hussain SS, Liu X, Windmueller R, Ying Y, Stewart KM, Oyster M, Christie JD, Diamond JM, Engelhardt JF, Cantu E, Rowe SM, Kotton DN, Chapman HA, Morrisey EE. Basil MC, et al. Nature. 2022 Apr;604(7904):120-126. doi: 10.1038/s41586-022-04552-0. Epub 2022 Mar 30. Nature. 2022. PMID: 35355013 Free PMC article.
Guided construction of single cell reference for human and mouse lung.
Guo M, Morley MP, Jiang C, Wu Y, Li G, Du Y, Zhao S, Wagner A, Cakar AC, Kouril M, Jin K, Gaddis N, Kitzmiller JA, Stewart K, Basil MC, Lin SM, Ying Y, Babu A, Wikenheiser-Brokamp KA, Mun KS, Naren AP, Clair G, Adkins JN, Pryhuber GS, Misra RS, Aronow BJ, Tickle TL, Salomonis N, Sun X, Morrisey EE, Whitsett JA; NHLBI LungMAP Consortium; Xu Y. Guo M, et al. Nat Commun. 2023 Jul 29;14(1):4566. doi: 10.1038/s41467-023-40173-5. Nat Commun. 2023. PMID: 37516747 Free PMC article.
16 results