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Lysosomes mediate the mitochondrial UPR via mTORC1-dependent ATF4 phosphorylation.
Cell Discov. 2023 Sep 7;9(1):92. doi: 10.1038/s41421-023-00589-1.
Cell Discov. 2023.
PMID: 37679337
Free PMC article.
A lysosomal surveillance response to stress extends healthspan.
Li TY, Gao AW, Yang R, Sun Y, Lei Y, Li X, Chen L, Liu YJ, Arey RN, Morales K, Liu RB, Wang W, Zhou A, Zhao TJ, Li W, Lalou A, Wang Q, Lima T, Houtkooper RH, Auwerx J.
Li TY, et al.
Nat Cell Biol. 2025 Jun 26. doi: 10.1038/s41556-025-01693-y. Online ahead of print.
Nat Cell Biol. 2025.
PMID: 40571723
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