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Simultaneous binding of Guidance Cues NET1 and RGM blocks extracellular NEO1 signaling.
Robinson RA, Griffiths SC, van de Haar LL, Malinauskas T, van Battum EY, Zelina P, Schwab RA, Karia D, Malinauskaite L, Brignani S, van den Munkhof MH, Düdükcü Ö, De Ruiter AA, Van den Heuvel DMA, Bishop B, Elegheert J, Aricescu AR, Pasterkamp RJ, Siebold C. Robinson RA, et al. Cell. 2021 Apr 15;184(8):2103-2120.e31. doi: 10.1016/j.cell.2021.02.045. Epub 2021 Mar 18. Cell. 2021. PMID: 33740419 Free PMC article.
Snapshots of actin and tubulin folding inside the TRiC chaperonin.
Kelly JJ, Tranter D, Pardon E, Chi G, Kramer H, Happonen L, Knee KM, Janz JM, Steyaert J, Bulawa C, Paavilainen VO, Huiskonen JT, Yue WW. Kelly JJ, et al. Nat Struct Mol Biol. 2022 May;29(5):420-429. doi: 10.1038/s41594-022-00755-1. Epub 2022 Apr 21. Nat Struct Mol Biol. 2022. PMID: 35449234 Free PMC article.
Potent cross-reactive antibodies following Omicron breakthrough in vaccinees.
Nutalai R, Zhou D, Tuekprakhon A, Ginn HM, Supasa P, Liu C, Huo J, Mentzer AJ, Duyvesteyn HME, Dijokaite-Guraliuc A, Skelly D, Ritter TG, Amini A, Bibi S, Adele S, Johnson SA, Constantinides B, Webster H, Temperton N, Klenerman P, Barnes E, Dunachie SJ, Crook D, Pollard AJ, Lambe T, Goulder P; OPTIC consortium, ISARIC4C consortium; Paterson NG, Williams MA, Hall DR, Mongkolsapaya J, Fry EE, Dejnirattisai W, Ren J, Stuart DI, Screaton GR. Nutalai R, et al. Cell. 2022 Jun 9;185(12):2116-2131.e18. doi: 10.1016/j.cell.2022.05.014. Epub 2022 May 20. Cell. 2022. PMID: 35662412 Free PMC article.
Bacteriophage PRD1 as a nanoscaffold for drug loading.
Duyvesteyn HME, Santos-Pérez I, Peccati F, Martinez-Castillo A, Walter TS, Reguera D, Goñi FM, Jiménez-Osés G, Oksanen HM, Stuart DI, Abrescia NGA. Duyvesteyn HME, et al. Nanoscale. 2021 Dec 13;13(47):19875-19883. doi: 10.1039/d1nr04153c. Nanoscale. 2021. PMID: 34851350 Free PMC article.
Structures and therapeutic potential of anti-RBD human monoclonal antibodies against SARS-CoV-2.
Huang KA, Zhou D, Tan TK, Chen C, Duyvesteyn HME, Zhao Y, Ginn HM, Qin L, Rijal P, Schimanski L, Donat R, Harding A, Gilbert-Jaramillo J, James W, Tree JA, Buttigieg K, Carroll M, Charlton S, Lien CE, Lin MY, Chen CP, Cheng SH, Chen X, Lin TY, Fry EE, Ren J, Ma C, Townsend AR, Stuart DI. Huang KA, et al. Theranostics. 2022 Jan 1;12(1):1-17. doi: 10.7150/thno.65563. eCollection 2022. Theranostics. 2022. PMID: 34987630 Free PMC article.
Phospho-regulation, nucleotide binding and ion access control in potassium-chloride cotransporters.
Chi G, Ebenhoch R, Man H, Tang H, Tremblay LE, Reggiano G, Qiu X, Bohstedt T, Liko I, Almeida FG, Garneau AP, Wang D, McKinley G, Moreau CP, Bountra KD, Abrusci P, Mukhopadhyay SMM, Fernandez-Cid A, Slimani S, Lavoie JL, Burgess-Brown NA, Tehan B, DiMaio F, Jazayeri A, Isenring P, Robinson CV, Dürr KL. Chi G, et al. EMBO J. 2021 Jul 15;40(14):e107294. doi: 10.15252/embj.2020107294. Epub 2021 May 25. EMBO J. 2021. PMID: 34031912 Free PMC article.
The antibody response to SARS-CoV-2 Beta underscores the antigenic distance to other variants.
Liu C, Zhou D, Nutalai R, Duyvesteyn HME, Tuekprakhon A, Ginn HM, Dejnirattisai W, Supasa P, Mentzer AJ, Wang B, Case JB, Zhao Y, Skelly DT, Chen RE, Johnson SA, Ritter TG, Mason C, Malik T, Temperton N, Paterson NG, Williams MA, Hall DR, Clare DK, Howe A, Goulder PJR, Fry EE, Diamond MS, Mongkolsapaya J, Ren J, Stuart DI, Screaton GR. Liu C, et al. Cell Host Microbe. 2022 Jan 12;30(1):53-68.e12. doi: 10.1016/j.chom.2021.11.013. Epub 2021 Nov 27. Cell Host Microbe. 2022. PMID: 34921776 Free PMC article.
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