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Increased RNA and Protein Degradation Is Required for Counteracting Transcriptional Burden and Proteotoxic Stress in Human Aneuploid Cells.
Cancer Discov. 2024 Dec 2;14(12):2532-2553. doi: 10.1158/2159-8290.CD-23-0309.
Cancer Discov. 2024.
PMID: 39247952
Free PMC article.
Transdifferentiation occurs without resetting development-specific DNA methylation, a key determinant of full-function cell identity.
Radwan A, Eccleston J, Sabag O, Marcus H, Sussman J, Ouro A, Rahamim M, Azagury M, Azria B, Stanger BZ, Cedar H, Buganim Y.
Radwan A, et al.
Proc Natl Acad Sci U S A. 2024 Sep 24;121(39):e2411352121. doi: 10.1073/pnas.2411352121. Epub 2024 Sep 18.
Proc Natl Acad Sci U S A. 2024.
PMID: 39292740
Free PMC article.
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