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HOIL-1L functions as the PKCζ ubiquitin ligase to promote lung tumor growth.
Queisser MA, Dada LA, Deiss-Yehiely N, Angulo M, Zhou G, Kouri FM, Knab LM, Liu J, Stegh AH, DeCamp MM, Budinger GR, Chandel NS, Ciechanover A, Iwai K, Sznajder JI. Queisser MA, et al. Am J Respir Crit Care Med. 2014 Sep 15;190(6):688-98. doi: 10.1164/rccm.201403-0463OC. Am J Respir Crit Care Med. 2014. PMID: 25118570 Free PMC article.
Follicle-stimulating hormone activation of hypoxia-inducible factor-1 by the phosphatidylinositol 3-kinase/AKT/Ras homolog enriched in brain (Rheb)/mammalian target of rapamycin (mTOR) pathway is necessary for induction of select protein markers of follicular differentiation.
Alam H, Maizels ET, Park Y, Ghaey S, Feiger ZJ, Chandel NS, Hunzicker-Dunn M. Alam H, et al. J Biol Chem. 2004 May 7;279(19):19431-40. doi: 10.1074/jbc.M401235200. Epub 2004 Feb 24. J Biol Chem. 2004. PMID: 14982927 Free PMC article.