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CDKN2A deletion remodels lipid metabolism to prime glioblastoma for ferroptosis.
Minami JK, Morrow D, Bayley NA, Fernandez EG, Salinas JJ, Tse C, Zhu H, Su B, Plawat R, Jones A, Sammarco A, Liau LM, Graeber TG, Williams KJ, Cloughesy TF, Dixon SJ, Bensinger SJ, Nathanson DA. Minami JK, et al. Cancer Cell. 2023 Jun 12;41(6):1048-1060.e9. doi: 10.1016/j.ccell.2023.05.001. Epub 2023 May 25. Cancer Cell. 2023. PMID: 37236196 Free PMC article.
CLSTN3β enforces adipocyte multilocularity to facilitate lipid utilization.
Qian K, Tol MJ, Wu J, Uchiyama LF, Xiao X, Cui L, Bedard AH, Weston TA, Rajendran PS, Vergnes L, Shimanaka Y, Yin Y, Jami-Alahmadi Y, Cohn W, Bajar BT, Lin CH, Jin B, DeNardo LA, Black DL, Whitelegge JP, Wohlschlegel JA, Reue K, Shivkumar K, Chen FJ, Young SG, Li P, Tontonoz P. Qian K, et al. Nature. 2023 Jan;613(7942):160-168. doi: 10.1038/s41586-022-05507-1. Epub 2022 Dec 7. Nature. 2023. PMID: 36477540 Free PMC article.
Metabolic programs of T cell tissue residency empower tumour immunity.
Reina-Campos M, Heeg M, Kennewick K, Mathews IT, Galletti G, Luna V, Nguyen Q, Huang H, Milner JJ, Hu KH, Vichaidit A, Santillano N, Boland BS, Chang JT, Jain M, Sharma S, Krummel MF, Chi H, Bensinger SJ, Goldrath AW. Reina-Campos M, et al. Nature. 2023 Sep;621(7977):179-187. doi: 10.1038/s41586-023-06483-w. Epub 2023 Aug 30. Nature. 2023. PMID: 37648857 Free PMC article.
Aster-dependent nonvesicular transport facilitates dietary cholesterol uptake.
Ferrari A, Whang E, Xiao X, Kennelly JP, Romartinez-Alonso B, Mack JJ, Weston T, Chen K, Kim Y, Tol MJ, Bideyan L, Nguyen A, Gao Y, Cui L, Bedard AH, Sandhu J, Lee SD, Fairall L, Williams KJ, Song W, Munguia P, Russell RA, Martin MG, Jung ME, Jiang H, Schwabe JWR, Young SG, Tontonoz P. Ferrari A, et al. Science. 2023 Nov 10;382(6671):eadf0966. doi: 10.1126/science.adf0966. Epub 2023 Nov 10. Science. 2023. PMID: 37943936 Free PMC article.
Hepatic nonvesicular cholesterol transport is critical for systemic lipid homeostasis.
Xiao X, Kennelly JP, Ferrari A, Clifford BL, Whang E, Gao Y, Qian K, Sandhu J, Jarrett KE, Brearley-Sholto MC, Nguyen A, Nagari RT, Lee MS, Zhang S, Weston TA, Young SG, Bensinger SJ, Villanueva CJ, de Aguiar Vallim TQ, Tontonoz P. Xiao X, et al. Nat Metab. 2023 Jan;5(1):165-181. doi: 10.1038/s42255-022-00722-6. Epub 2023 Jan 16. Nat Metab. 2023. PMID: 36646756 Free PMC article.
Toll-Like Receptors Induce Signal-Specific Reprogramming of the Macrophage Lipidome.
Hsieh WY, Zhou QD, York AG, Williams KJ, Scumpia PO, Kronenberger EB, Hoi XP, Su B, Chi X, Bui VL, Khialeeva E, Kaplan A, Son YM, Divakaruni AS, Sun J, Smale ST, Flavell RA, Bensinger SJ. Hsieh WY, et al. Cell Metab. 2020 Jul 7;32(1):128-143.e5. doi: 10.1016/j.cmet.2020.05.003. Epub 2020 Jun 8. Cell Metab. 2020. PMID: 32516576 Free PMC article.
Calculation of ATP production rates using the Seahorse XF Analyzer.
Desousa BR, Kim KK, Jones AE, Ball AB, Hsieh WY, Swain P, Morrow DH, Brownstein AJ, Ferrick DA, Shirihai OS, Neilson A, Nathanson DA, Rogers GW, Dranka BP, Murphy AN, Affourtit C, Bensinger SJ, Stiles L, Romero N, Divakaruni AS. Desousa BR, et al. EMBO Rep. 2023 Oct 9;24(10):e56380. doi: 10.15252/embr.202256380. Epub 2023 Aug 7. EMBO Rep. 2023. PMID: 37548091 Free PMC article.
Images in Lipid Research.
Young SG. Young SG. J Lipid Res. 2020 May;61(5):589-590. doi: 10.1194/jlr.E120000736. Epub 2020 Mar 4. J Lipid Res. 2020. PMID: 32132143 Free PMC article. No abstract available.
Cholesterol Transport to the Endoplasmic Reticulum.
Kennelly JP, Tontonoz P. Kennelly JP, et al. Cold Spring Harb Perspect Biol. 2023 Feb 1;15(2):a041263. doi: 10.1101/cshperspect.a041263. Cold Spring Harb Perspect Biol. 2023. PMID: 35940908 Free PMC article. Review.
66 results