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Year Number of Results
2017 1
2018 3
2019 23
2020 30
2021 39
2022 47
2023 44
2024 73
2025 44

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293 results

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Page 1
Targeting a neoantigen derived from a common TP53 mutation.
Hsiue EH, Wright KM, Douglass J, Hwang MS, Mog BJ, Pearlman AH, Paul S, DiNapoli SR, Konig MF, Wang Q, Schaefer A, Miller MS, Skora AD, Azurmendi PA, Murphy MB, Liu Q, Watson E, Li Y, Pardoll DM, Bettegowda C, Papadopoulos N, Kinzler KW, Vogelstein B, Gabelli SB, Zhou S. Hsiue EH, et al. Science. 2021 Mar 5;371(6533):eabc8697. doi: 10.1126/science.abc8697. Epub 2021 Mar 1. Science. 2021. PMID: 33649166 Free PMC article.
A Broad Spectrum Lasso Peptide Antibiotic Targeting the Bacterial Ribosome.
Wright G, Jangra M, Travin D, Aleksandrova E, Kaur M, Darwish L, Koteva K, Klepacki D, Wang W, Tiffany M, Sokaribo A, Coombes B, Vázquez-Laslop N, Polikanov Y, Mankin A. Wright G, et al. Res Sq [Preprint]. 2024 Sep 16:rs.3.rs-5058118. doi: 10.21203/rs.3.rs-5058118/v1. Res Sq. 2024. Update in: Nature. 2025 Apr;640(8060):1022-1030. doi: 10.1038/s41586-025-08723-7. PMID: 39372947 Free PMC article. Updated. Preprint.
Diffusing protein binders to intrinsically disordered proteins.
Liu C, Wu K, Choi H, Han H, Zhang X, Watson JL, Shijo S, Bera AK, Kang A, Brackenbrough E, Coventry B, Hick DR, Hoofnagle AN, Zhu P, Li X, Decarreau J, Gerben SR, Yang W, Wang X, Lamp M, Murray A, Bauer M, Baker D. Liu C, et al. bioRxiv [Preprint]. 2024 Jul 16:2024.07.16.603789. doi: 10.1101/2024.07.16.603789. bioRxiv. 2024. PMID: 39071267 Free PMC article. Preprint.
De novo designed proteins neutralize lethal snake venom toxins.
Torres SV, Valle MB, Mackessy SP, Menzies SK, Casewell NR, Ahmadi S, Burlet NJ, Muratspahić E, Sappington I, Overath MD, Rivera-de-Torre E, Ledergerber J, Laustsen AH, Boddum K, Bera AK, Kang A, Brackenbrough E, Cardoso IA, Crittenden EP, Edge RJ, Decarreau J, Ragotte RJ, Pillai AS, Abedi M, Han HL, Gerben SR, Murray A, Skotheim R, Stuart L, Stewart L, Fryer TJA, Jenkins TP, Baker D. Torres SV, et al. Res Sq [Preprint]. 2024 May 17:rs.3.rs-4402792. doi: 10.21203/rs.3.rs-4402792/v1. Res Sq. 2024. Update in: Nature. 2025 Mar;639(8053):225-231. doi: 10.1038/s41586-024-08393-x. PMID: 38798548 Free PMC article. Updated. Preprint.
Inhibitors of bacterial H2S biogenesis targeting antibiotic resistance and tolerance.
Shatalin K, Nuthanakanti A, Kaushik A, Shishov D, Peselis A, Shamovsky I, Pani B, Lechpammer M, Vasilyev N, Shatalina E, Rebatchouk D, Mironov A, Fedichev P, Serganov A, Nudler E. Shatalin K, et al. Science. 2021 Jun 11;372(6547):1169-1175. doi: 10.1126/science.abd8377. Science. 2021. PMID: 34112687 Free PMC article.
Binding and sensing diverse small molecules using shape-complementary pseudocycles.
An L, Said M, Tran L, Majumder S, Goreshnik I, Lee GR, Juergens D, Dauparas J, Anishchenko I, Coventry B, Bera AK, Kang A, Levine PM, Alvarez V, Pillai A, Norn C, Feldman D, Zorine D, Hicks DR, Li X, Sanchez MG, Vafeados DK, Salveson PJ, Vorobieva AA, Baker D. An L, et al. Science. 2024 Jul 19;385(6706):276-282. doi: 10.1126/science.adn3780. Epub 2024 Jul 18. Science. 2024. PMID: 39024436 Free PMC article.
De novo designed proteins neutralize lethal snake venom toxins.
Vázquez Torres S, Benard Valle M, Mackessy SP, Menzies SK, Casewell NR, Ahmadi S, Burlet NJ, Muratspahić E, Sappington I, Overath MD, Rivera-de-Torre E, Ledergerber J, Laustsen AH, Boddum K, Bera AK, Kang A, Brackenbrough E, Cardoso IA, Crittenden EP, Edge RJ, Decarreau J, Ragotte RJ, Pillai AS, Abedi M, Han HL, Gerben SR, Murray A, Skotheim R, Stuart L, Stewart L, Fryer TJA, Jenkins TP, Baker D. Vázquez Torres S, et al. Nature. 2025 Mar;639(8053):225-231. doi: 10.1038/s41586-024-08393-x. Epub 2025 Jan 15. Nature. 2025. PMID: 39814879 Free PMC article.
293 results