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Page 1
The informatics of ADNI.
Toga AW, Neu S, Sheehan ST, Crawford K; Alzheimer's Disease Neuroimaging Initiative. Toga AW, et al. Alzheimers Dement. 2024 Oct;20(10):7320-7330. doi: 10.1002/alz.14099. Epub 2024 Aug 14. Alzheimers Dement. 2024. PMID: 39140398 Free PMC article. Review.
The Informatics Core, centered at the Laboratory of Neuro Imaging (LONI), provides a comprehensive data hub that ensures data quality, accessibility, and security, fostering over 5600 publications and significant scientific advancements. ...
The Informatics Core, centered at the Laboratory of Neuro Imaging (LONI), provides a comprehensive data hub that ensures data quality …
Delineating three distinct spatiotemporal patterns of brain atrophy in Parkinson's disease.
Sakato Y, Shima A, Terada Y, Takeda K, Sakamaki-Tsukita H, Nishida A, Yoshimura K, Wada I, Furukawa K, Kambe D, Togo H, Mukai Y, Sawamura M, Nakanishi E, Yamakado H, Fushimi Y, Okada T, Takahashi Y, Nakamoto Y, Takahashi R, Hanakawa T, Sawamoto N. Sakato Y, et al. Brain. 2024 Nov 4;147(11):3702-3713. doi: 10.1093/brain/awae303. Brain. 2024. PMID: 39445741
Integrated cerebellar radiomic-network model for predicting mild cognitive impairment in Alzheimer's disease.
Chen Y, Qi Y, Hu Y, Qiu X, Qiu T, Li S, Liu M, Jia Q, Sun B, Liu C, Li T, Le W; Alzheimer's Disease Neuroimaging Initiative. Chen Y, et al. Alzheimers Dement. 2025 Jan;21(1):e14361. doi: 10.1002/alz.14361. Epub 2024 Nov 13. Alzheimers Dement. 2025. PMID: 39535490 Free PMC article.
METHODS: Radiomic features were extracted from magnetic resonance imaging (MRI) in the Alzheimer's Disease Neuroimaging Initiative (ADNI) dataset (n = 1319) and an in-house dataset (n = 308). ...
METHODS: Radiomic features were extracted from magnetic resonance imaging (MRI) in the Alzheimer's Disease Neuroimaging Initiative (A …
Utility of cerebrovascular imaging biomarkers to detect cerebral amyloidosis.
Howe MD, Caruso MR, Manoochehri M, Kunicki ZJ, Emrani S, Rudolph JL, Huey ED, Salloway SP, Oh H; Alzheimer's Disease Neuroimaging Initiative. Howe MD, et al. Alzheimers Dement. 2024 Oct;20(10):7220-7231. doi: 10.1002/alz.14207. Epub 2024 Sep 1. Alzheimers Dement. 2024. PMID: 39219209 Free PMC article.
We hypothesized that magnetic resonance imaging (MRI)-based CVD biomarkers-including cerebral microbleeds (CMBs), lacunar infarction, and white matter hyperintensities (WMHs)-would correlate with Abeta positivity on positron emission tomography (Abeta-PET). ...
We hypothesized that magnetic resonance imaging (MRI)-based CVD biomarkers-including cerebral microbleeds (CMBs), lacunar infarction, …
Biomarker pathway heterogeneity of amyloid-positive individuals.
Prosser L, Sudre CH, Oxtoby NP, Young AL, Malone IB, Manning EN, Pemberton H, Walsh P, Barkhof F, Biessels GJ, Cash DM, Barnes J; Alzheimer's Disease Neuroimaging Initiative. Prosser L, et al. Alzheimers Dement. 2024 Dec;20(12):8503-8515. doi: 10.1002/alz.14287. Epub 2024 Oct 17. Alzheimers Dement. 2024. PMID: 39417393 Free PMC article.
A genetic and proteomic comparison of key AD biomarkers across tissues.
Marsh TW, Western D, Timsina J, Gorijala P, Yang C, Pastor P, Liu M, Morris JC, Bateman RJ, Schindler SE, Sung YJ; Dominantly Inherited Alzheimer Network; Cruchaga C. Marsh TW, et al. Alzheimers Dement. 2024 Sep;20(9):6423-6440. doi: 10.1002/alz.14139. Epub 2024 Jul 30. Alzheimers Dement. 2024. PMID: 39077866 Free PMC article.
Global brain activity and its coupling with cerebrospinal fluid flow is related to tau pathology.
Han F, Lee J, Chen X, Ziontz J, Ward T, Landau SM, Baker SL, Harrison TM, Jagust WJ; Alzheimer's Disease Neuroimaging Initiative. Han F, et al. Alzheimers Dement. 2024 Dec;20(12):8541-8555. doi: 10.1002/alz.14296. Epub 2024 Nov 7. Alzheimers Dement. 2024. PMID: 39508716 Free PMC article.
This study links macroscale tau deposition in the human brain to cerebrospinal fluid (CSF) flow dynamics using resting-state functional magnetic resonance imaging (rsfMRI). METHODS: Low-frequency (< 0.1 Hz) resting-state global brain activity is coupled with CSF flow an …
This study links macroscale tau deposition in the human brain to cerebrospinal fluid (CSF) flow dynamics using resting-state functional magn …
Contributions of the ADNI Biostatistics Core.
Beckett LA, Saito N, Donohue MC, Harvey DJ; Alzheimer's Disease Neuroimaging Initiative. Beckett LA, et al. Alzheimers Dement. 2024 Oct;20(10):7331-7339. doi: 10.1002/alz.14159. Epub 2024 Aug 14. Alzheimers Dement. 2024. PMID: 39140601 Free PMC article. Review.
Stress testing the Centiloid: Precision and variability of PET quantification of amyloid pathology.
Shekari M, Vállez García D, Collij LE, Altomare D, Heeman F, Pemberton H, Roé Vellvé N, Bullich S, Buckley C, Stephens A, Farrar G, Frisoni G, Klunk WE, Barkhof F, Gispert JD; ADNI and the AMYPAD consortium. Shekari M, et al. Alzheimers Dement. 2024 Aug;20(8):5102-5113. doi: 10.1002/alz.13883. Epub 2024 Jul 4. Alzheimers Dement. 2024. PMID: 38961808 Free PMC article.
METHODS: We included 533 participants from AMYloid imaging to Prevent Alzheimer's Disease (AMYPAD DPMS) and Alzheimer's Disease Neuroimaging Initiative (ADNI) cohorts. ...The standard CL pipeline is robust against atrophy and image resolution variation. Estimated wi …
METHODS: We included 533 participants from AMYloid imaging to Prevent Alzheimer's Disease (AMYPAD DPMS) and Alzheimer's Disease Neuro …
38 results