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APOE4 leads to blood-brain barrier dysfunction predicting cognitive decline.
Montagne A, Nation DA, Sagare AP, Barisano G, Sweeney MD, Chakhoyan A, Pachicano M, Joe E, Nelson AR, D'Orazio LM, Buennagel DP, Harrington MG, Benzinger TLS, Fagan AM, Ringman JM, Schneider LS, Morris JC, Reiman EM, Caselli RJ, Chui HC, Tcw J, Chen Y, Pa J, Conti PS, Law M, Toga AW, Zlokovic BV. Montagne A, et al. Nature. 2020 May;581(7806):71-76. doi: 10.1038/s41586-020-2247-3. Epub 2020 Apr 29. Nature. 2020. PMID: 32376954 Free PMC article.
Blood-brain barrier breakdown is an early biomarker of human cognitive dysfunction.
Nation DA, Sweeney MD, Montagne A, Sagare AP, D'Orazio LM, Pachicano M, Sepehrband F, Nelson AR, Buennagel DP, Harrington MG, Benzinger TLS, Fagan AM, Ringman JM, Schneider LS, Morris JC, Chui HC, Law M, Toga AW, Zlokovic BV. Nation DA, et al. Nat Med. 2019 Feb;25(2):270-276. doi: 10.1038/s41591-018-0297-y. Epub 2019 Jan 14. Nat Med. 2019. PMID: 30643288 Free PMC article.
Lung endothelium, tau, and amyloids in health and disease.
Balczon R, Lin MT, Voth S, Nelson AR, Schupp JC, Wagener BM, Pittet JF, Stevens T. Balczon R, et al. Physiol Rev. 2024 Apr 1;104(2):533-587. doi: 10.1152/physrev.00006.2023. Epub 2023 Aug 10. Physiol Rev. 2024. PMID: 37561137 Free PMC article. Review.
Global rural health disparities in Alzheimer's disease and related dementias: State of the science.
Wiese LAK, Gibson A, Guest MA, Nelson AR, Weaver R, Gupta A, Carmichael O, Lewis JP, Lindauer A, Loi S, Peterson R, Radford K, Rhodus EK, Wong CG, Zuelsdorff M, Saidi LG, Valdivieso-Mora E, Franzen S, Pope CN, Killian TS, Shrestha HL, Heyn PC, Ng TKS, Prusaczyk B, John S, Kulshreshtha A, Sheffler JL, Besser L, Daniel V, Tolea MI, Miller J, Musyimi C, Corkey J, Yank V, Williams CL, Rahemi Z, Park J, Magzamen S, Newton RL Jr, Harrington C, Flatt JD, Arora S, Walter S, Griffin P, Babulal GM. Wiese LAK, et al. Alzheimers Dement. 2023 Sep;19(9):4204-4225. doi: 10.1002/alz.13104. Epub 2023 May 23. Alzheimers Dement. 2023. PMID: 37218539 Free PMC article. Review.
Gamma secretase activating protein promotes end-organ dysfunction after bacterial pneumonia.
Gwin MS, Alexeyev MF, Geurts AM, Lee JY, Zhou C, Yang XM, Cohen MV, Downey JM, Barrington RA, Spadafora D, Audia JP, Frank DW, Voth S, Pastukh VV, Bell J, Ayers L, Tambe DT, Nelson AR, Balczon R, Lin MT, Stevens T. Gwin MS, et al. Am J Physiol Lung Cell Mol Physiol. 2023 Aug 1;325(2):L174-L189. doi: 10.1152/ajplung.00018.2023. Epub 2023 Jun 27. Am J Physiol Lung Cell Mol Physiol. 2023. PMID: 37366533 Free PMC article.
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