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A genetic and proteomic comparison of key AD biomarkers across tissues.
Marsh TW, Western D, Timsina J, Gorijala P, Yang C, Pastor P, Liu M, Morris JC, Bateman RJ, Schindler SE, Sung YJ; Dominantly Inherited Alzheimer Network; Cruchaga C. Marsh TW, et al. Alzheimers Dement. 2024 Sep;20(9):6423-6440. doi: 10.1002/alz.14139. Epub 2024 Jul 30. Alzheimers Dement. 2024. PMID: 39077866 Free PMC article.
Novel early-onset Alzheimer-associated genes influence risk through dysregulation of glutamate, immune activation, and intracellular signaling pathways.
Bradley J, Pottier C, da Fonseca EL, Kurup JT, Western D, Wang C, Neupane A, Ray NR, Jean-Francois M, Ali M, Timsina J, Bergmann K, Budde J, Martin ER, Pericak-Vance MA, Cuccaro M, Naj AC, Kunkle BW; Alzheimer's Disease Genetics Consortium (ADGC), Charles F. and Joanne Knight Alzheimer Disease Research Center (Knight‐ADRC); Schellenberg GD, Fernandez V, Haines J, Morris JC, Holtzman DM, Perrin RJ, Reitz C, Beecham GW, Cruchaga C. Bradley J, et al. Alzheimers Dement. 2025 Jun;21(6):e70377. doi: 10.1002/alz.70377. Alzheimers Dement. 2025. PMID: 40556318 Free PMC article.