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Page 1
The 2022 symposium on dementia and brain aging in low- and middle-income countries: Highlights on research, diagnosis, care, and impact.
Kalaria R, Maestre G, Mahinrad S, Acosta DM, Akinyemi RO, Alladi S, Allegri RF, Arshad F, Babalola DO, Baiyewu O, Bak TH, Bellaj T, Brodie-Mends DK, Carrillo MC, Celestin KK, Damasceno A, de Silva RK, de Silva R, Djibuti M, Dreyer AJ, Ellajosyula R, Farombi TH, Friedland RP, Garza N, Gbessemehlan A, Georgiou EE, Govia I, Grinberg LT, Guerchet M, Gugssa SA, Gumikiriza-Onoria JL, Hogervorst E, Hornberger M, Ibanez A, Ihara M, Issac TG, Jönsson L, Karanja WM, Lee JH, Leroi I, Livingston G, Manes FF, Mbakile-Mahlanza L, Miller BL, Musyimi CW, Mutiso VN, Nakasujja N, Ndetei DM, Nightingale S, Novotni G, Nyamayaro P, Nyame S, Ogeng'o JA, Ogunniyi A, de Oliveira MO, Okubadejo NU, Orrell M, Paddick SM, Pericak-Vance MA, Pirtosek Z, Potocnik FCV, Raman R, Rizig M, Rosselli M, Salokhiddinov M, Satizabal CL, Sepulveda-Falla D, Seshadri S, Sexton CE, Skoog I, George-Hyslop PHS, Suemoto CK, Thapa P, Udeh-Momoh CT, Valcour V, Vance JM, Varghese M, Vera JH, Walker RW, Zetterberg H, Zewde YZ, Ismail O. Kalaria R, et al. Alzheimers Dement. 2024 Jun;20(6):4290-4314. doi: 10.1002/alz.13836. Epub 2024 May 2. Alzheimers Dement. 2024. PMID: 38696263 Free PMC article. Review.
A global view of the genetic basis of Alzheimer disease.
Reitz C, Pericak-Vance MA, Foroud T, Mayeux R. Reitz C, et al. Nat Rev Neurol. 2023 May;19(5):261-277. doi: 10.1038/s41582-023-00789-z. Epub 2023 Apr 6. Nat Rev Neurol. 2023. PMID: 37024647 Free PMC article. Review.
Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies LRRC4C, LHX5-AS1 and nominates ancestry-specific loci PTPRK , GRB14 , and KIAA0825 as novel risk loci for Alzheimer's disease: the Alzheimer's Disease Genetics Consortium.
Rajabli F, Benchek P, Tosto G, Kushch N, Sha J, Bazemore K, Zhu C, Lee WP, Haut J, Hamilton-Nelson KL, Wheeler NR, Zhao Y, Farrell JJ, Grunin MA, Leung YY, Kuksa PP, Li D, Lucio da Fonseca E, Mez JB, Palmer EL, Pillai J, Sherva RM, Song YE, Zhang X, Iqbal T, Pathak O, Valladares O, Kuzma AB, Abner E, Adams PM, Aguirre A, Albert MS, Albin RL, Allen M, Alvarez L, Apostolova LG, Arnold SE, Asthana S, Atwood CS, Ayres G, Baldwin CT, Barber RC, Barnes LL, Barral S, Beach TG, Becker JT, Beecham GW, Beekly D, Benitez BA, Bennett D, Bertelson J, Bird TD, Blacker D, Boeve BF, Bowen JD, Boxer A, Brewer J, Burke JR, Burns JM, Buxbaum JD, Cairns NJ, Cantwell LB, Cao C, Carlson CS, Carlsson CM, Carney RM, Carrasquillo MM, Chasse S, Chesselet MF, Chin NA, Chui HC, Chung J, Craft S, Crane PK, Cribbs DH, Crocco EA, Cruchaga C, Cuccaro ML, Cullum M, Darby E, Davis B, De Jager PL, DeCarli C, DeToledo J, Dick M, Dickson DW, Dombroski BA, Doody RS, Duara R, Ertekin-Taner N, Evans DA, Faber KM, Fairchild TJ, Fallon KB, Fardo DW, Farlow MR, Fernandez-Hernandez V, Ferris S, Foroud TM, Frosch MP, Fulton-Howard B, Galasko DR, Gamboa A, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Goate AM, Grabowski TJ,… See abstract for full author list ➔ Rajabli F, et al. medRxiv [Preprint]. 2023 Jul 8:2023.07.06.23292311. doi: 10.1101/2023.07.06.23292311. medRxiv. 2023. PMID: 37461624 Free PMC article. Preprint.
Associations of Sex, Race, and Apolipoprotein E Alleles With Multiple Domains of Cognition Among Older Adults.
Walters S, Contreras AG, Eissman JM, Mukherjee S, Lee ML, Choi SE, Scollard P, Trittschuh EH, Mez JB, Bush WS, Kunkle BW, Naj AC, Peterson A, Gifford KA, Cuccaro ML, Cruchaga C, Pericak-Vance MA, Farrer LA, Wang LS, Haines JL, Jefferson AL, Kukull WA, Keene CD, Saykin AJ, Thompson PM, Martin ER, Bennett DA, Barnes LL, Schneider JA, Crane PK, Hohman TJ, Dumitrescu L; Alzheimer’s Disease Neuroimaging Initiative, Alzheimer’s Disease Genetics Consortium, and Alzheimer’s Disease Sequencing Project. Walters S, et al. JAMA Neurol. 2023 Sep 1;80(9):929-939. doi: 10.1001/jamaneurol.2023.2169. JAMA Neurol. 2023. PMID: 37459083 Free PMC article.
Comparing Alzheimer's genes in African, European, and Amerindian induced pluripotent stem cell-derived microglia.
Moura S, Nasciben LB, Ramirez AM, Coombs L, Rivero J, Van Booven DJ, DeRosa BA, Hamilton-Nelson KL, Whitehead PL, Adams LD, Starks TD, Mena PR, Illanes-Manrique M, Tejada S, Byrd GS, Cornejo-Olivas MR, Feliciano-Astacio BE, Nuytemans K, Wang L, Pericak-Vance MA, Dykxhoorn DM, Rajabli F, Griswold AJ, Young JI, Vance JM. Moura S, et al. Alzheimers Dement. 2025 Feb;21(2):e70031. doi: 10.1002/alz.70031. Alzheimers Dement. 2025. PMID: 40008916 Free PMC article.
The liquid-to-solid transition of FUS is promoted by the condensate surface.
Shen Y, Chen A, Wang W, Shen Y, Ruggeri FS, Aime S, Wang Z, Qamar S, Espinosa JR, Garaizar A, St George-Hyslop P, Collepardo-Guevara R, Weitz DA, Vigolo D, Knowles TPJ. Shen Y, et al. Proc Natl Acad Sci U S A. 2023 Aug 15;120(33):e2301366120. doi: 10.1073/pnas.2301366120. Epub 2023 Aug 7. Proc Natl Acad Sci U S A. 2023. PMID: 37549257 Free PMC article.
Association of common and rare variants with Alzheimer's disease in more than 13,000 diverse individuals with whole-genome sequencing from the Alzheimer's Disease Sequencing Project.
Lee WP, Choi SH, Shea MG, Cheng PL, Dombroski BA, Pitsillides AN, Heard-Costa NL, Wang H, Bulekova K, Kuzma AB, Leung YY, Farrell JJ, Lin H, Kunkle BW, Naj A, Blue EE, Nusetor F, Wang D, Boerwinkle E, Bush WS, Zhang X, De Jager PL, Dupuis J, Farrer LA, Fornage M, Martin E, Pericak-Vance M, Seshadri S, Wijsman EM, Wang LS; Alzheimer's Disease Sequencing Project; Schellenberg GD, Destefano AL, Haines JL, Peloso GM. Lee WP, et al. Alzheimers Dement. 2024 Dec;20(12):8470-8483. doi: 10.1002/alz.14283. Epub 2024 Oct 20. Alzheimers Dement. 2024. PMID: 39428839 Free PMC article.
APOE and Alzheimer's disease and related dementias risk among 12,221 Hispanics/Latinos.
Barral S, Yang Z, Phillips N, Barber RC, Brickman AM, Honig LS, Cieza B, Reyes-Dumeyer D, Mayeux R, Rajabli F, Cuccaro ML, Vance JM, Arango SM, Samper-Ternent R, Obregon AM, Montesinos R, Soto-Añari M, Duran JC, Cusicanqui M, Velazquez IZJ, Marca V, Illanes-Manrique M, Cornejo-Olivas M, Pericak-Vance M, Wong R, O'Bryant S, Custodio N, Tosto G. Barral S, et al. Alzheimers Dement. 2025 Apr;21(4):e70138. doi: 10.1002/alz.70138. Alzheimers Dement. 2025. PMID: 40219824 Free PMC article.
African origin haplotype protective for Alzheimer's disease in APOEε4 carriers: exploring potential mechanisms.
Bertholim-Nasciben L, Nuytemans K, Van Booven D, Rajabli F, Moura S, Ramirez AM, Dykxhoorn DM, Wang L, Scott WK, Davis DA, Vontell RT, McInerney KF, Cuccaro ML, Byrd GS, Haines JL, Gearing M, Adams LD, Pericak-Vance MA; ADSP; Young JI, Griswold AJ, Vance JM. Bertholim-Nasciben L, et al. bioRxiv [Preprint]. 2024 Oct 27:2024.10.24.619909. doi: 10.1101/2024.10.24.619909. bioRxiv. 2024. PMID: 39484566 Free PMC article. Preprint.
Generalizability of tau and amyloid plasma biomarkers in Alzheimer's disease cohorts of diverse genetic ancestries.
Griswold AJ, Rajabli F, Gu T, Arvizu J, Golightly CG, Whitehead PL, Hamilton-Nelson KL, Adams LD, Sanchez JJ, Mena PR, Starks TD, Illanes-Manrique M, Silva C, Bush WS, Cuccaro ML, Vance JM, Cornejo-Olivas MR, Feliciano-Astacio BE, Byrd GS, Beecham GW, Haines JL, Pericak-Vance MA. Griswold AJ, et al. Alzheimers Dement. 2025 Mar;21(3):e14367. doi: 10.1002/alz.14367. Alzheimers Dement. 2025. PMID: 40133765 Free PMC article.
24 results