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A global view of the genetic basis of Alzheimer disease.
Reitz C, Pericak-Vance MA, Foroud T, Mayeux R. Reitz C, et al. Nat Rev Neurol. 2023 May;19(5):261-277. doi: 10.1038/s41582-023-00789-z. Epub 2023 Apr 6. Nat Rev Neurol. 2023. PMID: 37024647 Free PMC article. Review.
Rare genetic variation in fibronectin 1 (FN1) protects against APOEε4 in Alzheimer's disease.
Bhattarai P, Gunasekaran TI, Belloy ME, Reyes-Dumeyer D, Jülich D, Tayran H, Yilmaz E, Flaherty D, Turgutalp B, Sukumar G, Alba C, McGrath EM, Hupalo DN, Bacikova D, Le Guen Y, Lantigua R, Medrano M, Rivera D, Recio P, Nuriel T, Ertekin-Taner N, Teich AF, Dickson DW, Holley S, Greicius M, Dalgard CL, Zody M, Mayeux R, Kizil C, Vardarajan BN. Bhattarai P, et al. Acta Neuropathol. 2024 Apr 10;147(1):70. doi: 10.1007/s00401-024-02721-1. Acta Neuropathol. 2024. PMID: 38598053 Free PMC article.
Gliovascular transcriptional perturbations in Alzheimer's disease reveal molecular mechanisms of blood brain barrier dysfunction.
İş Ö, Wang X, Reddy JS, Min Y, Yilmaz E, Bhattarai P, Patel T, Bergman J, Quicksall Z, Heckman MG, Tutor-New FQ, Can Demirdogen B, White L, Koga S, Krause V, Inoue Y, Kanekiyo T, Cosacak MI, Nelson N, Lee AJ, Vardarajan B, Mayeux R, Kouri N, Deniz K, Carnwath T, Oatman SR, Lewis-Tuffin LJ, Nguyen T; Alzheimer’s Disease Neuroimaging Initiative; Carrasquillo MM, Graff-Radford J, Petersen RC, Jr Jack CR, Kantarci K, Murray ME, Nho K, Saykin AJ, Dickson DW, Kizil C, Allen M, Ertekin-Taner N. İş Ö, et al. Nat Commun. 2024 Jun 20;15(1):4758. doi: 10.1038/s41467-024-48926-6. Nat Commun. 2024. PMID: 38902234 Free PMC article.
Associations among plasma, MRI, and amyloid PET biomarkers of Alzheimer's disease and related dementias and the impact of health-related comorbidities in a community-dwelling cohort.
Rudolph MD, Sutphen CL, Register TC, Whitlow CT, Solingapuram Sai KK, Hughes TM, Bateman JR, Dage JL, Russ KA, Mielke MM, Craft S, Lockhart SN. Rudolph MD, et al. Alzheimers Dement. 2024 Jun;20(6):4159-4173. doi: 10.1002/alz.13835. Epub 2024 May 15. Alzheimers Dement. 2024. PMID: 38747525 Free PMC article.
Epigenetic and genetic risk of Alzheimer disease from autopsied brains in two ethnic groups.
Ma Y, Reyes-Dumeyer D, Piriz A, Recio P, Mejia DR, Medrano M, Lantigua RA, Vonsattel JPG, Tosto G, Teich AF, Ciener B, Leskinen S, Sivakumar S, DeTure M, Ranjan D, Dickson D, Murray M, Lee E, Wolk DA, Jin LW, Dugger BN, Hiniker A, Rissman RA, Mayeux R, Vardarajan BN. Ma Y, et al. Acta Neuropathol. 2024 Aug 23;148(1):27. doi: 10.1007/s00401-024-02778-y. Acta Neuropathol. 2024. PMID: 39177846 Free PMC article.
Considerations in the clinical use of amyloid PET and CSF biomarkers for Alzheimer's disease.
Leuzy A, Bollack A, Pellegrino D, Teunissen CE, La Joie R, Rabinovici GD, Franzmeier N, Johnson K, Barkhof F, Shaw LM, Arkhipenko A, Schindler SE, Honig LS, Moscoso Rial A, Schöll M, Zetterberg H, Blennow K, Hansson O, Farrar G. Leuzy A, et al. Alzheimers Dement. 2025 Mar;21(3):e14528. doi: 10.1002/alz.14528. Alzheimers Dement. 2025. PMID: 40042435 Free PMC article. Review.
53 results