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Eliciting a single amino acid change by vaccination generates antibody protection against group 1 and group 2 influenza A viruses.
Ray R, Nait Mohamed FA, Maurer DP, Huang J, Alpay BA, Ronsard L, Xie Z, Han J, Fernandez-Quintero M, Phan QA, Ursin RL, Vu M, Kirsch KH, Prum T, Rosado VC, Bracamonte-Moreno T, Okonkwo V, Bals J, McCarthy C, Nair U, Kanekiyo M, Ward AB, Schmidt AG, Batista FD, Lingwood D. Ray R, et al. Immunity. 2024 May 14;57(5):1141-1159.e11. doi: 10.1016/j.immuni.2024.03.022. Epub 2024 Apr 25. Immunity. 2024. PMID: 38670113 Free PMC article.
Modulating the immunodominance hierarchy of immunoglobulin germline-encoded structural motifs targeting the influenza hemagglutinin stem.
Ataca S, Sangesland M, de Paiva Fróes Rocha R, Torrents de la Peña A, Ronsard L, Boyoglu-Barnum S, Gillespie RA, Tsybovsky Y, Stephens T, Moin SM, Lederhofer J, Creanga A, Andrews SF, Barnes RM, Rohrer D, Lonberg N, Graham BS, Ward AB, Lingwood D, Kanekiyo M. Ataca S, et al. Cell Rep. 2024 Dec 24;43(12):114990. doi: 10.1016/j.celrep.2024.114990. Epub 2024 Nov 22. Cell Rep. 2024. PMID: 39580804 Free PMC article.
Engineering an Antibody V Gene-Selective Vaccine.
Ronsard L, Yousif AS, Peabody J, Okonkwo V, Devant P, Mogus AT, Barnes RM, Rohrer D, Lonberg N, Peabody D, Chackerian B, Lingwood D. Ronsard L, et al. Front Immunol. 2021 Sep 9;12:730471. doi: 10.3389/fimmu.2021.730471. eCollection 2021. Front Immunol. 2021. PMID: 34566992 Free PMC article.
DNA origami vaccines program antigen-focused germinal centers.
Romanov A, Knappe GA, Ronsard L, Suh H, Omer M, Chapman AP, Lewis VR, Spivakovsky K, Canales J, Reizis B, Tingle RD, Cottrell CA, Schiffner T, Lingwood D, Bathe M, Irvine DJ. Romanov A, et al. bioRxiv [Preprint]. 2025 Mar 1:2025.02.21.639354. doi: 10.1101/2025.02.21.639354. bioRxiv. 2025. PMID: 40060683 Free PMC article. Preprint.
COVID-19-neutralizing antibodies predict disease severity and survival.
Garcia-Beltran WF, Lam EC, Astudillo MG, Yang D, Miller TE, Feldman J, Hauser BM, Caradonna TM, Clayton KL, Nitido AD, Murali MR, Alter G, Charles RC, Dighe A, Branda JA, Lennerz JK, Lingwood D, Schmidt AG, Iafrate AJ, Balazs AB. Garcia-Beltran WF, et al. Cell. 2021 Jan 21;184(2):476-488.e11. doi: 10.1016/j.cell.2020.12.015. Epub 2020 Dec 15. Cell. 2021. PMID: 33412089 Free PMC article.
28 results