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25 results

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Page 1
SIRT6 Suppresses Pancreatic Cancer through Control of Lin28b.
Kugel S, Sebastián C, Fitamant J, Ross KN, Saha SK, Jain E, Gladden A, Arora KS, Kato Y, Rivera MN, Ramaswamy S, Sadreyev RI, Goren A, Deshpande V, Bardeesy N, Mostoslavsky R. Kugel S, et al. Cell. 2016 Jun 2;165(6):1401-1415. doi: 10.1016/j.cell.2016.04.033. Epub 2016 May 12. Cell. 2016. PMID: 27180906 Free PMC article.
Metabolism, longevity and epigenetics.
Cosentino C, Mostoslavsky R. Cosentino C, et al. Cell Mol Life Sci. 2013 May;70(9):1525-41. doi: 10.1007/s00018-013-1295-3. Epub 2013 Mar 7. Cell Mol Life Sci. 2013. PMID: 23467663 Free PMC article. Review.
Chromatin and beyond: the multitasking roles for SIRT6.
Kugel S, Mostoslavsky R. Kugel S, et al. Trends Biochem Sci. 2014 Feb;39(2):72-81. doi: 10.1016/j.tibs.2013.12.002. Epub 2014 Jan 14. Trends Biochem Sci. 2014. PMID: 24438746 Free PMC article. Review.
Sirtuins, metabolism, and DNA repair.
Choi JE, Mostoslavsky R. Choi JE, et al. Curr Opin Genet Dev. 2014 Jun;26:24-32. doi: 10.1016/j.gde.2014.05.005. Epub 2014 Jul 5. Curr Opin Genet Dev. 2014. PMID: 25005742 Free PMC article. Review.
The role of mammalian sirtuins in cancer metabolism.
Sebastián C, Mostoslavsky R. Sebastián C, et al. Semin Cell Dev Biol. 2015 Jul;43:33-42. doi: 10.1016/j.semcdb.2015.07.008. Epub 2015 Jul 31. Semin Cell Dev Biol. 2015. PMID: 26238985 Review.
Neuroprotective Functions for the Histone Deacetylase SIRT6.
Kaluski S, Portillo M, Besnard A, Stein D, Einav M, Zhong L, Ueberham U, Arendt T, Mostoslavsky R, Sahay A, Toiber D. Kaluski S, et al. Cell Rep. 2017 Mar 28;18(13):3052-3062. doi: 10.1016/j.celrep.2017.03.008. Cell Rep. 2017. PMID: 28355558 Free PMC article.
The Histone Deacetylase SIRT6 Restrains Transcription Elongation via Promoter-Proximal Pausing.
Etchegaray JP, Zhong L, Li C, Henriques T, Ablondi E, Nakadai T, Van Rechem C, Ferrer C, Ross KN, Choi JE, Samarakkody A, Ji F, Chang A, Sadreyev RI, Ramaswamy S, Nechaev S, Whetstine JR, Roeder RG, Adelman K, Goren A, Mostoslavsky R. Etchegaray JP, et al. Mol Cell. 2019 Aug 22;75(4):683-699.e7. doi: 10.1016/j.molcel.2019.06.034. Epub 2019 Aug 6. Mol Cell. 2019. PMID: 31399344 Free PMC article.
A unique subset of glycolytic tumour-propagating cells drives squamous cell carcinoma.
Choi JE, Sebastian C, Ferrer CM, Lewis CA, Sade-Feldman M, LaSalle T, Gonye A, Lopez BGC, Abdelmoula WM, Regan MS, Cetinbas M, Pascual G, Wojtkiewicz GR, Silveira GG, Boon R, Ross KN, Tirosh I, Saladi SV, Ellisen LW, Sadreyev RI, Benitah SA, Agar NYR, Hacohen N, Mostoslavsky R. Choi JE, et al. Nat Metab. 2021 Feb;3(2):182-195. doi: 10.1038/s42255-021-00350-6. Epub 2021 Feb 22. Nat Metab. 2021. PMID: 33619381 Free PMC article.
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