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Year Number of Results
2016 3
2017 5
2018 2
2019 6
2020 6
2021 4
2022 7
2023 8
2024 1
2025 0

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38 results

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Page 1
A selective BCL-XL PROTAC degrader achieves safe and potent antitumor activity.
Khan S, Zhang X, Lv D, Zhang Q, He Y, Zhang P, Liu X, Thummuri D, Yuan Y, Wiegand JS, Pei J, Zhang W, Sharma A, McCurdy CR, Kuruvilla VM, Baran N, Ferrando AA, Kim YM, Rogojina A, Houghton PJ, Huang G, Hromas R, Konopleva M, Zheng G, Zhou D. Khan S, et al. Nat Med. 2019 Dec;25(12):1938-1947. doi: 10.1038/s41591-019-0668-z. Epub 2019 Dec 2. Nat Med. 2019. PMID: 31792461 Free PMC article.
Cellular Responses to Widespread DNA Replication Stress.
Nickoloff JA, Jaiswal AS, Sharma N, Williamson EA, Tran MT, Arris D, Yang M, Hromas R. Nickoloff JA, et al. Int J Mol Sci. 2023 Nov 29;24(23):16903. doi: 10.3390/ijms242316903. Int J Mol Sci. 2023. PMID: 38069223 Free PMC article. Review.
Crucial roles of the BRCA1-BARD1 E3 ubiquitin ligase activity in homology-directed DNA repair.
Wang M, Li W, Tomimatsu N, Yu CH, Ji JH, Alejo S, Witus SR, Alimbetov D, Fitzgerald O, Wu B, Wang Q, Huang Y, Gan Y, Dong F, Kwon Y, Sareddy GR, Curiel TJ, Habib AA, Hromas R, Dos Santos Passos C, Yao T, Ivanov DN, Brzovic PS, Burma S, Klevit RE, Zhao W. Wang M, et al. Mol Cell. 2023 Oct 19;83(20):3679-3691.e8. doi: 10.1016/j.molcel.2023.09.015. Epub 2023 Oct 4. Mol Cell. 2023. PMID: 37797621 Free PMC article.
Structural insights into BCDX2 complex function in homologous recombination.
Rawal Y, Jia L, Meir A, Zhou S, Kaur H, Ruben EA, Kwon Y, Bernstein KA, Jasin M, Taylor AB, Burma S, Hromas R, Mazin AV, Zhao W, Zhou D, Wasmuth EV, Greene EC, Sung P, Olsen SK. Rawal Y, et al. Nature. 2023 Jul;619(7970):640-649. doi: 10.1038/s41586-023-06219-w. Epub 2023 Jun 21. Nature. 2023. PMID: 37344589 Free PMC article.
Interaction between APC and Fen1 during breast carcinogenesis.
Narayan S, Jaiswal AS, Law BK, Kamal MA, Sharma AK, Hromas RA. Narayan S, et al. DNA Repair (Amst). 2016 May;41:54-62. doi: 10.1016/j.dnarep.2016.04.003. Epub 2016 Apr 7. DNA Repair (Amst). 2016. PMID: 27088617 Free PMC article. Review.
DNA binding and RAD51 engagement by the BRCA2 C-terminus orchestrate DNA repair and replication fork preservation.
Kwon Y, Rösner H, Zhao W, Selemenakis P, He Z, Kawale AS, Katz JN, Rogers CM, Neal FE, Badamchi Shabestari A, Petrosius V, Singh AK, Joel MZ, Lu L, Holloway SP, Burma S, Mukherjee B, Hromas R, Mazin A, Wiese C, Sørensen CS, Sung P. Kwon Y, et al. Nat Commun. 2023 Jan 26;14(1):432. doi: 10.1038/s41467-023-36211-x. Nat Commun. 2023. PMID: 36702902 Free PMC article.
TATDN2 resolution of R-loops is required for survival of BRCA1-mutant cancer cells.
Jaiswal AS, Dutta A, Srinivasan G, Yuan Y, Zhou D, Shaheen M, Sadideen DT, Kirby A, Williamson EA, Gupta YK, Olsen SK, Xu M, Loranc E, Mukhopadhyay P, Pertsemlidis A, Bishop AJR, Sung P, Nickoloff JA, Hromas R. Jaiswal AS, et al. Nucleic Acids Res. 2023 Dec 11;51(22):12224-12241. doi: 10.1093/nar/gkad952. Nucleic Acids Res. 2023. PMID: 37953292 Free PMC article.
38 results