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Page 1
DYNLL1 binds to MRE11 to limit DNA end resection in BRCA1-deficient cells.
He YJ, Meghani K, Caron MC, Yang C, Ronato DA, Bian J, Sharma A, Moore J, Niraj J, Detappe A, Doench JG, Legube G, Root DE, D'Andrea AD, Drané P, De S, Konstantinopoulos PA, Masson JY, Chowdhury D. He YJ, et al. Nature. 2018 Nov;563(7732):522-526. doi: 10.1038/s41586-018-0670-5. Epub 2018 Oct 31. Nature. 2018. PMID: 30464262 Free PMC article.
NEAT1 modulates the TIRR/53BP1 complex to maintain genome integrity.
Kilgas S, Syed A, Toolan-Kerr P, Swift ML, Roychoudhury S, Sarkar A, Wilkins S, Quigley M, Poetsch AR, Botuyan MV, Cui G, Mer G, Ule J, Drané P, Chowdhury D. Kilgas S, et al. Nat Commun. 2024 Sep 30;15(1):8438. doi: 10.1038/s41467-024-52862-w. Nat Commun. 2024. PMID: 39349456 Free PMC article.
TIRR inhibits the 53BP1-p53 complex to alter cell-fate programs.
Parnandi N, Rendo V, Cui G, Botuyan MV, Remisova M, Nguyen H, Drané P, Beroukhim R, Altmeyer M, Mer G, Chowdhury D. Parnandi N, et al. Mol Cell. 2021 Jun 17;81(12):2583-2595.e6. doi: 10.1016/j.molcel.2021.03.039. Epub 2021 May 6. Mol Cell. 2021. PMID: 33961797 Free PMC article.
CDK phosphorylation of TRF2 controls t-loop dynamics during the cell cycle.
Sarek G, Kotsantis P, Ruis P, Van Ly D, Margalef P, Borel V, Zheng XF, Flynn HR, Snijders AP, Chowdhury D, Cesare AJ, Boulton SJ. Sarek G, et al. Nature. 2019 Nov;575(7783):523-527. doi: 10.1038/s41586-019-1744-8. Epub 2019 Nov 13. Nature. 2019. PMID: 31723267 Free PMC article.
12 results