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ERα-associated translocations underlie oncogene amplifications in breast cancer.
Lee JJ, Jung YL, Cheong TC, Espejo Valle-Inclan J, Chu C, Gulhan DC, Ljungström V, Jin H, Viswanadham VV, Watson EV, Cortés-Ciriano I, Elledge SJ, Chiarle R, Pellman D, Park PJ. Lee JJ, et al. Nature. 2023 Jun;618(7967):1024-1032. doi: 10.1038/s41586-023-06057-w. Epub 2023 May 17. Nature. 2023. PMID: 37198482 Free PMC article.
ALK in cancer: from function to therapeutic targeting.
Voena C, Ambrogio C, Iannelli F, Chiarle R. Voena C, et al. Nat Rev Cancer. 2025 May;25(5):359-378. doi: 10.1038/s41568-025-00797-9. Epub 2025 Mar 7. Nat Rev Cancer. 2025. PMID: 40055571 Review.
DNA repair mechanisms that promote insertion-deletion events during immunoglobulin gene diversification.
Hao Q, Zhan C, Lian C, Luo S, Cao W, Wang B, Xie X, Ye X, Gui T, Voena C, Pighi C, Wang Y, Tian Y, Wang X, Dai P, Cai Y, Liu X, Ouyang S, Sun S, Hu Q, Liu J, Ye Y, Zhao J, Lu A, Wang JY, Huang C, Su B, Meng FL, Chiarle R, Pan-Hammarström Q, Yeap LS. Hao Q, et al. Sci Immunol. 2023 Mar 31;8(81):eade1167. doi: 10.1126/sciimmunol.ade1167. Epub 2023 Mar 24. Sci Immunol. 2023. PMID: 36961908 Free PMC article.
Genomic and biological study of fusion genes as resistance mechanisms to EGFR inhibitors.
Kobayashi Y, Oxnard GR, Cohen EF, Mahadevan NR, Alessi JV, Hung YP, Bertram AA, Heppner DE, Ribeiro MF, Sacardo KP, Saddi R, Macedo MP, Blasco RB, Li J, Kurppa KJ, Nguyen T, Voligny E, Ananda G, Chiarle R, Katz A, Tolstorukov MY, Sholl LM, Jänne PA. Kobayashi Y, et al. Nat Commun. 2022 Sep 24;13(1):5614. doi: 10.1038/s41467-022-33210-2. Nat Commun. 2022. PMID: 36153311 Free PMC article.
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