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DNA hypomethylation silences anti-tumor immune genes in early prostate cancer and CTCs.
Guo H, Vuille JA, Wittner BS, Lachtara EM, Hou Y, Lin M, Zhao T, Raman AT, Russell HC, Reeves BA, Pleskow HM, Wu CL, Gnirke A, Meissner A, Efstathiou JA, Lee RJ, Toner M, Aryee MJ, Lawrence MS, Miyamoto DT, Maheswaran S, Haber DA. Guo H, et al. Cell. 2023 Jun 22;186(13):2765-2782.e28. doi: 10.1016/j.cell.2023.05.028. Epub 2023 Jun 15. Cell. 2023. PMID: 37327786 Free PMC article.
ATM deficiency confers specific therapeutic vulnerabilities in bladder cancer.
Zhou Y, Börcsök J, Adib E, Kamran SC, Neil AJ, Stawiski K, Freeman D, Stormoen DR, Sztupinszki Z, Samant A, Nassar A, Bekele RT, Hanlon T, Valentine H, Epstein I, Sharma B, Felt K, Abbosh P, Wu CL, Efstathiou JA, Miyamoto DT, Anderson W, Szallasi Z, Mouw KW. Zhou Y, et al. Sci Adv. 2023 Nov 24;9(47):eadg2263. doi: 10.1126/sciadv.adg2263. Epub 2023 Nov 22. Sci Adv. 2023. PMID: 37992168 Free PMC article.
Genomic Tumor Correlates of Clinical Outcomes Following Organ-Sparing Chemoradiation Therapy for Bladder Cancer.
Kamran SC, Zhou Y, Otani K, Drumm M, Otani Y, Wu S, Wu CL, Feldman AS, Wszolek M, Lee RJ, Saylor PJ, Lennerz J, Van Allen E, Willers H, Hong TS, Liu Y, Davicioni E, Gibb EA, Shipley WU, Mouw KW, Efstathiou JA, Miyamoto DT. Kamran SC, et al. Clin Cancer Res. 2023 Dec 15;29(24):5116-5127. doi: 10.1158/1078-0432.CCR-23-0792. Clin Cancer Res. 2023. PMID: 37870965 Free PMC article.
Predictive Model of Acute Rectal Toxicity in Prostate Cancer Treated With Radiotherapy.
Shah KD, Yeap BY, Lee H, Soetan ZO, Moteabbed M, Muise S, Cowan J, Remillard K, Silvia B, Mendenhall NP, Soffen E, Mishra MV, Kamran SC, Miyamoto DT, Paganetti H, Efstathiou JA, Chamseddine I. Shah KD, et al. JCO Clin Cancer Inform. 2025 Mar;9:e2400252. doi: 10.1200/CCI-24-00252. Epub 2025 Mar 19. JCO Clin Cancer Inform. 2025. PMID: 40106736
Prognostic Significance of Immune Cell Infiltration in Muscle-invasive Bladder Cancer Treated with Definitive Chemoradiation: A Secondary Analysis of RTOG 0524 and RTOG 0712.
Rana Z, Kamran SC, Shetty AC, Sutera P, Song Y, Bazyar S, Solanki AA, Simko JP, Pollack A, McConkey D, Kates M, Siddiqui MM, Hiken J, Earls J, Messina D, Mouw KW, Miyamoto D, Shipley WU, Michaelson MD, Zietman A, Coen JJ, Dahl DM, Jani AB, Souhami L, Chang BK, Lee RJ, Pham H, Marshall DT, Shen X, Pugh SL, Feng FY, Efstathiou JA, Tran PT, Deek MP. Rana Z, et al. Eur Urol Oncol. 2024 Oct;7(5):986-989. doi: 10.1016/j.euo.2024.03.015. Epub 2024 Apr 18. Eur Urol Oncol. 2024. PMID: 38641541