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The colibactin-producing Escherichia coli alters the tumor microenvironment to immunosuppressive lipid overload facilitating colorectal cancer progression and chemoresistance.
de Oliveira Alves N, Dalmasso G, Nikitina D, Vaysse A, Ruez R, Ledoux L, Pedron T, Bergsten E, Boulard O, Autier L, Allam S, Motreff L, Sauvanet P, Letourneur D, Kashyap P, Gagnière J, Pezet D, Godfraind C, Salzet M, Lemichez E, Bonnet M, Najjar I, Malabat C, Monot M, Mestivier D, Barnich N, Yadav P, Fournier I, Kennedy S, Mettouchi A, Bonnet R, Sobhani I, Chamaillard M. de Oliveira Alves N, et al. Gut Microbes. 2024 Jan-Dec;16(1):2320291. doi: 10.1080/19490976.2024.2320291. Epub 2024 Feb 28. Gut Microbes. 2024. PMID: 38417029 Free PMC article.
Colonic Epithelial Circadian Disruption Worsens Dextran Sulfate Sodium-Induced Colitis.
Jochum SB, Engen PA, Shaikh M, Naqib A, Wilber S, Raeisi S, Zhang L, Song S, Sanzo G, Chouhan V, Ko F, Post Z, Tran L, Ramirez V, Green SJ, Khazaie K, Hayden DM, Brown MJ, Voigt RM, Forsyth CB, Keshavarzian A, Swanson GR. Jochum SB, et al. Inflamm Bowel Dis. 2023 Mar 1;29(3):444-457. doi: 10.1093/ibd/izac219. Inflamm Bowel Dis. 2023. PMID: 36287037 Free PMC article.
Colorectal cancer-associated microbiota contributes to oncogenic epigenetic signatures.
Sobhani I, Bergsten E, Couffin S, Amiot A, Nebbad B, Barau C, de'Angelis N, Rabot S, Canoui-Poitrine F, Mestivier D, Pédron T, Khazaie K, Sansonetti PJ. Sobhani I, et al. Proc Natl Acad Sci U S A. 2019 Nov 26;116(48):24285-24295. doi: 10.1073/pnas.1912129116. Epub 2019 Nov 11. Proc Natl Acad Sci U S A. 2019. PMID: 31712445 Free PMC article.