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The IL6/JAK/STAT3 signaling axis is a therapeutic vulnerability in SMARCB1-deficient bladder cancer.
Amara CS, Kami Reddy KR, Yuntao Y, Chan YS, Piyarathna DWB, Dobrolecki LE, Shih DJH, Shi Z, Xu J, Huang S, Ellis MJ, Apolo AB, Ballester LY, Gao J, Hansel DE, Lotan Y, Hodges HC, Lerner SP, Creighton CJ, Sreekumar A, Zheng WJ, Msaouel P, Kavuri SM, Putluri N. Amara CS, et al. Nat Commun. 2024 Feb 14;15(1):1373. doi: 10.1038/s41467-024-45132-2. Nat Commun. 2024. PMID: 38355560 Free PMC article.
Mitochondrial reprogramming by activating OXPHOS via glutamine metabolism in African American patients with bladder cancer.
Kami Reddy KR, Piyarathna DWB, Park JH, Putluri V, Amara CS, Kamal AHM, Xu J, Kraushaar D, Huang S, Jung SY, Eberlin LS, Johnson JR, Kittles RA, Ballester LY, Parsawar K, Siddiqui MM, Gao J, Langer Gramer A, Bollag RJ, Terris MK, Lotan Y, Creighton CJ, Lerner SP, Sreekumar A, Kaipparettu BA, Putluri N. Kami Reddy KR, et al. JCI Insight. 2024 Sep 10;9(17):e172336. doi: 10.1172/jci.insight.172336. JCI Insight. 2024. PMID: 39253977 Free PMC article.
The genomic alterations in glioblastoma influence the levels of CSF metabolites.
Wang DH, Fujita Y, Dono A, Rodriguez Armendariz AG, Shah M, Putluri N, Pichardo-Rojas PS, Patel CB, Zhu JJ, Huse JT, Parker Kerrigan BC, Lang FF, Esquenazi Y, Ballester LY. Wang DH, et al. Acta Neuropathol Commun. 2024 Jan 19;12(1):13. doi: 10.1186/s40478-024-01722-1. Acta Neuropathol Commun. 2024. PMID: 38243318 Free PMC article.
Role of adenosine deaminase in prostate cancer progression.
Charles C, Lloyd SM, Piyarathna DWB, Gohlke J, Rasaily U, Putluri V, Simons BW, Zaslavsky A, Nallandhighal S, Michailidis G, Palanisamy N, Navone N, Jones JA, Ittmann MM, Putluri N, Rowley DR, Salami SS, Palapattu GS, Sreekumar A. Charles C, et al. Am J Clin Exp Urol. 2023 Dec 15;11(6):594-612. eCollection 2023. Am J Clin Exp Urol. 2023. PMID: 38148936 Free PMC article.
Resolving tissue complexity by multimodal spatial omics modeling with MISO.
Coleman K, Schroeder A, Loth M, Zhang D, Park JH, Sung JY, Blank N, Cowan AJ, Qian X, Chen J, Jiang J, Yan H, Samarah LZ, Clemenceau JR, Jang I, Kim M, Barnfather I, Rabinowitz JD, Deng Y, Lee EB, Lazar A, Gao J, Furth EE, Hwang TH, Wang L, Thaiss CA, Hu J, Li M. Coleman K, et al. Nat Methods. 2025 Mar;22(3):530-538. doi: 10.1038/s41592-024-02574-2. Epub 2025 Jan 15. Nat Methods. 2025. PMID: 39815104
Bypassing cisplatin resistance in Nrf2 hyperactivated head and neck cancer through effective PI3Kinase targeting.
Yadollahi P, McCord KA, Li Y, Dayoub H, Saab K, Essien F, Hyslop S, Kan E, Ahmed KM, Kirby PR, Putluri V, Ambati CSR, Kami Reddy KR, Castro P, Skinner HD, Coarfa C, Decker WK, Osman AA, Patel R, Myers JN, Lai SY, Putluri N, Johnson FM, Frederick MJ, Hudson WH, Sandulache VC. Yadollahi P, et al. bioRxiv [Preprint]. 2025 Jan 16:2025.01.10.632413. doi: 10.1101/2025.01.10.632413. bioRxiv. 2025. PMID: 39868226 Free PMC article. Preprint.