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Page 1
FGF23 directly inhibits osteoprogenitor differentiation in Dmp1-knockout mice.
Courbon G, Kentrup D, Thomas JJ, Wang X, Tsai HH, Spindler J, Von Drasek J, Ndjonko LM, Martinez-Calle M, Lynch S, Hivert L, Wang X, Chang W, Feng JQ, David V, Martin A. Courbon G, et al. JCI Insight. 2023 Dec 22;8(24):e156850. doi: 10.1172/jci.insight.156850. JCI Insight. 2023. PMID: 37943605 Free PMC article.
PTH/PTHrP Receptor Signaling, Allostery, and Structures.
Sutkeviciute I, Clark LJ, White AD, Gardella TJ, Vilardaga JP. Sutkeviciute I, et al. Trends Endocrinol Metab. 2019 Nov;30(11):860-874. doi: 10.1016/j.tem.2019.07.011. Trends Endocrinol Metab. 2019. PMID: 31699241 Free PMC article. Review.
Calcium-sensing receptor-mediated NLRP3 inflammasome response to calciprotein particles drives inflammation in rheumatoid arthritis.
Jäger E, Murthy S, Schmidt C, Hahn M, Strobel S, Peters A, Stäubert C, Sungur P, Venus T, Geisler M, Radusheva V, Raps S, Rothe K, Scholz R, Jung S, Wagner S, Pierer M, Seifert O, Chang W, Estrela-Lopis I, Raulien N, Krohn K, Sträter N, Hoeppener S, Schöneberg T, Rossol M, Wagner U. Jäger E, et al. Nat Commun. 2020 Aug 25;11(1):4243. doi: 10.1038/s41467-020-17749-6. Nat Commun. 2020. PMID: 32843625 Free PMC article.
Precise druggability of the PTH type 1 receptor.
Sutkeviciute I, Lee JY, White AD, Maria CS, Peña KA, Savransky S, Doruker P, Li H, Lei S, Kaynak B, Tu C, Clark LJ, Sanker S, Gardella TJ, Chang W, Bahar I, Vilardaga JP. Sutkeviciute I, et al. Nat Chem Biol. 2022 Mar;18(3):272-280. doi: 10.1038/s41589-021-00929-w. Epub 2021 Dec 23. Nat Chem Biol. 2022. PMID: 34949836 Free PMC article.
37 results