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VEGFA mRNA-LNP promotes biliary epithelial cell-to-hepatocyte conversion in acute and chronic liver diseases and reverses steatosis and fibrosis.
Rizvi F, Lee YR, Diaz-Aragon R, Bawa PS, So J, Florentino RM, Wu S, Sarjoo A, Truong E, Smith AR, Wang F, Everton E, Ostrowska A, Jung K, Tam Y, Muramatsu H, Pardi N, Weissman D, Soto-Gutierrez A, Shin D, Gouon-Evans V. Rizvi F, et al. Cell Stem Cell. 2023 Dec 7;30(12):1640-1657.e8. doi: 10.1016/j.stem.2023.10.008. Epub 2023 Nov 28. Cell Stem Cell. 2023. PMID: 38029740 Free PMC article.
Update on Hepatobiliary Plasticity.
Kim M, Rizvi F, Shin D, Gouon-Evans V. Kim M, et al. Semin Liver Dis. 2023 Feb;43(1):13-23. doi: 10.1055/s-0042-1760306. Epub 2023 Feb 10. Semin Liver Dis. 2023. PMID: 36764306 Free PMC article.
c-Maf: The magic wand that turns on LSEC fate.
Smith AR, Gouon-Evans V. Smith AR, et al. Cell Stem Cell. 2022 Apr 7;29(4):491-493. doi: 10.1016/j.stem.2022.03.011. Cell Stem Cell. 2022. PMID: 35395181 Free article.
Transient growth factor expression via mRNA in lipid nanoparticles promotes hepatocyte cell therapy to treat murine liver diseases.
Smith AR, Rizvi F, Everton E, Adeagbo A, Wu S, Tam Y, Muramatsu H, Pardi N, Weissman D, Gouon-Evans V. Smith AR, et al. bioRxiv [Preprint]. 2024 Jan 11:2024.01.11.575286. doi: 10.1101/2024.01.11.575286. bioRxiv. 2024. Update in: Nat Commun. 2024 Jun 12;15(1):5010. doi: 10.1038/s41467-024-49332-8. PMID: 38260488 Free PMC article. Updated. Preprint.