R01 DK125859/DK/NIDDK NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2021	5
2022	7
2023	10
2024	15
2025	9

1

Molecular mechanisms of dietary restriction promoting health and longevity.

Green CL, Lamming DW, Fontana L. Green CL, et al. Nat Rev Mol Cell Biol. 2022 Jan;23(1):56-73. doi: 10.1038/s41580-021-00411-4. Epub 2021 Sep 13. Nat Rev Mol Cell Biol. 2022. PMID: 34518687 Free PMC article. Review.

2

Targeting the biology of aging with mTOR inhibitors.

Mannick JB, Lamming DW. Mannick JB, et al. Nat Aging. 2023 Jun;3(6):642-660. doi: 10.1038/s43587-023-00416-y. Epub 2023 May 4. Nat Aging. 2023. PMID: 37142830 Free PMC article. Review.

3

The central moTOR of metabolism.

Simcox J, Lamming DW. Simcox J, et al. Dev Cell. 2022 Mar 28;57(6):691-706. doi: 10.1016/j.devcel.2022.02.024. Epub 2022 Mar 21. Dev Cell. 2022. PMID: 35316619 Free PMC article. Review.

4

Dietary restriction of isoleucine increases healthspan and lifespan of genetically heterogeneous mice.

Green CL, Trautman ME, Chaiyakul K, Jain R, Alam YH, Babygirija R, Pak HH, Sonsalla MM, Calubag MF, Yeh CY, Bleicher A, Novak G, Liu TT, Newman S, Ricke WA, Matkowskyj KA, Ong IM, Jang C, Simcox J, Lamming DW. Green CL, et al. Cell Metab. 2023 Nov 7;35(11):1976-1995.e6. doi: 10.1016/j.cmet.2023.10.005. Cell Metab. 2023. PMID: 37939658 Free PMC article.

5

A nutrigeroscience approach: Dietary macronutrients and cellular senescence.

Calubag MF, Robbins PD, Lamming DW. Calubag MF, et al. Cell Metab. 2024 Sep 3;36(9):1914-1944. doi: 10.1016/j.cmet.2024.07.025. Epub 2024 Aug 22. Cell Metab. 2024. PMID: 39178854 Review.

6

When a calorie is not just a calorie: Diet quality and timing as mediators of metabolism and healthy aging.

Mihaylova MM, Chaix A, Delibegovic M, Ramsey JJ, Bass J, Melkani G, Singh R, Chen Z, Ja WW, Shirasu-Hiza M, Latimer MN, Mattison JA, Thalacker-Mercer AE, Dixit VD, Panda S, Lamming DW. Mihaylova MM, et al. Cell Metab. 2023 Jul 11;35(7):1114-1131. doi: 10.1016/j.cmet.2023.06.008. Epub 2023 Jun 30. Cell Metab. 2023. PMID: 37392742 Free PMC article. Review.

7

Fasting drives the metabolic, molecular and geroprotective effects of a calorie-restricted diet in mice.

Pak HH, Haws SA, Green CL, Koller M, Lavarias MT, Richardson NE, Yang SE, Dumas SN, Sonsalla M, Bray L, Johnson M, Barnes S, Darley-Usmar V, Zhang J, Yen CE, Denu JM, Lamming DW. Pak HH, et al. Nat Metab. 2021 Oct;3(10):1327-1341. doi: 10.1038/s42255-021-00466-9. Epub 2021 Oct 18. Nat Metab. 2021. PMID: 34663973 Free PMC article.

8

Geroprotector drugs and exercise: friends or foes on healthy longevity?

Elliehausen CJ, Anderson RM, Diffee GM, Rhoads TW, Lamming DW, Hornberger TA, Konopka AR. Elliehausen CJ, et al. BMC Biol. 2023 Dec 8;21(1):287. doi: 10.1186/s12915-023-01779-9. BMC Biol. 2023. PMID: 38066609 Free PMC article. Review.

9

Protein restriction slows the development and progression of pathology in a mouse model of Alzheimer's disease.

Babygirija R, Sonsalla MM, Mill J, James I, Han JH, Green CL, Calubag MF, Wade G, Tobon A, Michael J, Trautman MM, Matoska R, Yeh CY, Grunow I, Pak HH, Rigby MJ, Baldwin DA, Niemi NM, Denu JM, Puglielli L, Simcox J, Lamming DW. Babygirija R, et al. Nat Commun. 2024 Jun 18;15(1):5217. doi: 10.1038/s41467-024-49589-z. Nat Commun. 2024. PMID: 38890307 Free PMC article.

10

Late-life protein or isoleucine restriction impacts physiological and molecular signatures of aging.

Yeh CY, Chini LCS, Davidson JW, Garcia GG, Gallagher MS, Freichels IT, Calubag MF, Rodgers AC, Green CL, Babygirija R, Sonsalla MM, Pak HH, Trautman ME, Hacker TA, Miller RA, Simcox JA, Lamming DW. Yeh CY, et al. Nat Aging. 2024 Dec;4(12):1760-1771. doi: 10.1038/s43587-024-00744-7. Epub 2024 Nov 27. Nat Aging. 2024. PMID: 39604703 Free PMC article.

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