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2022 5
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Autophagy in age-related macular degeneration.
Kaarniranta K, Blasiak J, Liton P, Boulton M, Klionsky DJ, Sinha D. Kaarniranta K, et al. Autophagy. 2023 Feb;19(2):388-400. doi: 10.1080/15548627.2022.2069437. Epub 2022 May 1. Autophagy. 2023. PMID: 35468037 Free PMC article. Review.
Increased LCN2 (lipocalin 2) in the RPE decreases autophagy and activates inflammasome-ferroptosis processes in a mouse model of dry AMD.
Gupta U, Ghosh S, Wallace CT, Shang P, Xin Y, Nair AP, Yazdankhah M, Strizhakova A, Ross MA, Liu H, Hose S, Stepicheva NA, Chowdhury O, Nemani M, Maddipatla V, Grebe R, Das M, Lathrop KL, Sahel JA, Zigler JS Jr, Qian J, Ghosh A, Sergeev Y, Handa JT, St Croix CM, Sinha D. Gupta U, et al. Autophagy. 2023 Jan;19(1):92-111. doi: 10.1080/15548627.2022.2062887. Epub 2022 Apr 26. Autophagy. 2023. PMID: 35473441 Free PMC article.
Lysosomes in retinal health and disease.
Boya P, Kaarniranta K, Handa JT, Sinha D. Boya P, et al. Trends Neurosci. 2023 Dec;46(12):1067-1082. doi: 10.1016/j.tins.2023.09.006. Epub 2023 Oct 16. Trends Neurosci. 2023. PMID: 37848361 Free PMC article. Review.
The AKT2/SIRT5/TFEB pathway as a potential therapeutic target in non-neovascular AMD.
Ghosh S, Sharma R, Bammidi S, Koontz V, Nemani M, Yazdankhah M, Kedziora KM, Stolz DB, Wallace CT, Yu-Wei C, Franks J, Bose D, Shang P, Ambrosino HM, Dutton JR, Geng Z, Montford J, Ryu J, Rajasundaram D, Hose S, Sahel JA, Puertollano R, Finkel T, Zigler JS Jr, Sergeev Y, Watkins SC, Goetzman ES, Ferrington DA, Flores-Bellver M, Kaarniranta K, Sodhi A, Bharti K, Handa JT, Sinha D. Ghosh S, et al. Nat Commun. 2024 Jul 21;15(1):6150. doi: 10.1038/s41467-024-50500-z. Nat Commun. 2024. PMID: 39034314 Free PMC article.
Thermal Shift Assay in Ferroptosis.
Bammidi S, Hose S, Handa JT, Sinha D, Ghosh S. Bammidi S, et al. Methods Mol Biol. 2023;2712:179-186. doi: 10.1007/978-1-0716-3433-2_16. Methods Mol Biol. 2023. PMID: 37578706 Free PMC article.
Activated mTOR Signaling in the RPE Drives EMT, Autophagy, and Metabolic Disruption, Resulting in AMD-Like Pathology in Mice.
Chowdhury O, Bammidi S, Gautam P, Babu VS, Liu H, Shang P, Xin Y, Mahally E, Nemani M, Koontz V, Lathrop K, Kedziora KM, Franks J, Sun M, Smith JW, DeVine LR, Cole RN, Stepicheva N, Strizhakova A, Chattopadhyay S, Hose S, Zigler JS Jr, Sahel JA, Qian J, Guha P, Handa JT, Ghosh S, Sinha D. Chowdhury O, et al. Aging Cell. 2025 Jun;24(6):e70018. doi: 10.1111/acel.70018. Epub 2025 Feb 17. Aging Cell. 2025. PMID: 39957408 Free PMC article.
15 results