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Lysosomes in retinal health and disease.
Boya P, Kaarniranta K, Handa JT, Sinha D. Boya P, et al. Trends Neurosci. 2023 Dec;46(12):1067-1082. doi: 10.1016/j.tins.2023.09.006. Epub 2023 Oct 16. Trends Neurosci. 2023. PMID: 37848361 Free PMC article. Review.
The AKT2/SIRT5/TFEB pathway as a potential therapeutic target in non-neovascular AMD.
Ghosh S, Sharma R, Bammidi S, Koontz V, Nemani M, Yazdankhah M, Kedziora KM, Stolz DB, Wallace CT, Yu-Wei C, Franks J, Bose D, Shang P, Ambrosino HM, Dutton JR, Geng Z, Montford J, Ryu J, Rajasundaram D, Hose S, Sahel JA, Puertollano R, Finkel T, Zigler JS Jr, Sergeev Y, Watkins SC, Goetzman ES, Ferrington DA, Flores-Bellver M, Kaarniranta K, Sodhi A, Bharti K, Handa JT, Sinha D. Ghosh S, et al. Nat Commun. 2024 Jul 21;15(1):6150. doi: 10.1038/s41467-024-50500-z. Nat Commun. 2024. PMID: 39034314 Free PMC article.
Neutrophils in Ocular Diseases.
Bammidi S, Koontz V, Gautam P, Hose S, Sinha D, Ghosh S. Bammidi S, et al. Int J Mol Sci. 2024 Jul 15;25(14):7736. doi: 10.3390/ijms25147736. Int J Mol Sci. 2024. PMID: 39062975 Free PMC article. Review.
Thermal Shift Assay in Ferroptosis.
Bammidi S, Hose S, Handa JT, Sinha D, Ghosh S. Bammidi S, et al. Methods Mol Biol. 2023;2712:179-186. doi: 10.1007/978-1-0716-3433-2_16. Methods Mol Biol. 2023. PMID: 37578706 Free PMC article.
Activated mTOR Signaling in the RPE Drives EMT, Autophagy, and Metabolic Disruption, Resulting in AMD-Like Pathology in Mice.
Chowdhury O, Bammidi S, Gautam P, Babu VS, Liu H, Shang P, Xin Y, Mahally E, Nemani M, Koontz V, Lathrop K, Kedziora KM, Franks J, Sun M, Smith JW, DeVine LR, Cole RN, Stepicheva N, Strizhakova A, Chattopadhyay S, Hose S, Zigler JS Jr, Sahel JA, Qian J, Guha P, Handa JT, Ghosh S, Sinha D. Chowdhury O, et al. Aging Cell. 2025 Jun;24(6):e70018. doi: 10.1111/acel.70018. Epub 2025 Feb 17. Aging Cell. 2025. PMID: 39957408 Free PMC article.
Attenuated adenosine mediated immune-dampening increases natural killer cell activity in early age-related macular degeneration.
Nair AP, Ghosh S, Babu VS, Praveen M, Xin Y, Sahu GR, Vaidya TA, Debnath J, Raja K, Gadde SGK, M B T, Shetty N, Saxena A, Shetty R, Hose S, Deshpande V, Chakrabarty K, Handa JT, Qian JJ, Sethu S, Sinha D, Ghosh A. Nair AP, et al. bioRxiv [Preprint]. 2025 Jan 27:2025.01.22.634301. doi: 10.1101/2025.01.22.634301. bioRxiv. 2025. PMID: 39975064 Free PMC article. Preprint.