R01 GM068118/GM/NIGMS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2006	2
2008	1
2009	3
2010	1
2012	3
2013	1
2014	1
2015	1
2016	1
2017	3
2018	3
2019	1
2021	1
2022	1
2023	3
2024	1
2025	1

1

Bone morphogenetic protein signaling: the pathway and its regulation.

Akiyama T, Raftery LA, Wharton KA. Akiyama T, et al. Genetics. 2024 Feb 7;226(2):iyad200. doi: 10.1093/genetics/iyad200. Genetics. 2024. PMID: 38124338 Free PMC article. Review.

2

Heterodimerization-dependent secretion of bone morphogenetic proteins in Drosophila.

Bauer M, Aguilar G, Wharton KA, Matsuda S, Affolter M. Bauer M, et al. Dev Cell. 2023 Apr 24;58(8):645-659.e4. doi: 10.1016/j.devcel.2023.03.008. Epub 2023 Apr 12. Dev Cell. 2023. PMID: 37054707 Free PMC article.

3

Fine-tuned shuttles for bone morphogenetic proteins.

Wharton KA, Serpe M. Wharton KA, et al. Curr Opin Genet Dev. 2013 Aug;23(4):374-84. doi: 10.1016/j.gde.2013.04.012. Epub 2013 Jun 2. Curr Opin Genet Dev. 2013. PMID: 23735641 Free PMC article. Review.

4

BMP/TGF-β signaling as a modulator of neurodegeneration in ALS.

Russo K, Wharton KA. Russo K, et al. Dev Dyn. 2022 Jan;251(1):10-25. doi: 10.1002/dvdy.333. Epub 2021 Mar 29. Dev Dyn. 2022. PMID: 33745185 Free PMC article.

5

MuSK Regulates Neuromuscular Junction Nav1.4 Localization and Excitability.

Fish LA, Ewing MD, Rich KA, Xi C, Chen I, Jaime D, Madigan LA, Wang X, Shahtout JL, Feder RE, Funai K, Christian JL, Wharton KA, Rich MM, Arnold WD, Fallon JR. Fish LA, et al. J Neurosci. 2025 Apr 9;45(15):e1279232025. doi: 10.1523/JNEUROSCI.1279-23.2025. J Neurosci. 2025. PMID: 39880682

6

Drosophila models of FOP provide mechanistic insight.

Le V, Anderson E, Akiyama T, Wharton KA. Le V, et al. Bone. 2018 Apr;109:192-200. doi: 10.1016/j.bone.2017.11.001. Epub 2017 Nov 8. Bone. 2018. PMID: 29128351 Free PMC article.

7

The MuSK-BMP pathway regulates synaptic Nav1.4 localization and muscle excitability.

Fish LA, Ewing MD, Jaime D, Rich KA, Xi C, Wang X, Feder RE, Wharton KA, Rich MM, Arnold WD, Fallon JR. Fish LA, et al. bioRxiv [Preprint]. 2023 Oct 29:2023.10.24.563837. doi: 10.1101/2023.10.24.563837. bioRxiv. 2023. PMID: 37961580 Free PMC article. Preprint.

8

Polypeptide Substrate Accessibility Hypothesis: Gain-of-Function R206H Mutation Allosterically Affects Activin Receptor-like Protein Kinase Activity.

Groppe JC, Lu G, Tandang-Silvas MR, Pathi A, Konda S, Wu J, Le VQ, Culbert AL, Shore EM, Wharton KA, Kaplan FS. Groppe JC, et al. Biomolecules. 2023 Jul 14;13(7):1129. doi: 10.3390/biom13071129. Biomolecules. 2023. PMID: 37509165 Free PMC article.

9

TGFbeta family signaling: novel insights in development and disease.

Wharton K, Derynck R. Wharton K, et al. Development. 2009 Nov;136(22):3691-7. doi: 10.1242/dev.040584. Development. 2009. PMID: 19855012

10

A large bioactive BMP ligand with distinct signaling properties is produced by alternative proconvertase processing.

Akiyama T, Marqués G, Wharton KA. Akiyama T, et al. Sci Signal. 2012 Apr 3;5(218):ra28. doi: 10.1126/scisignal.2002549. Sci Signal. 2012. PMID: 22472650 Free PMC article.

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