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Page 1
Intestinal microbiota controls graft-versus-host disease independent of donor-host genetic disparity.
Koyama M, Hippe DS, Srinivasan S, Proll SC, Miltiadous O, Li N, Zhang P, Ensbey KS, Hoffman NG, Schmidt CR, Yeh AC, Minnie SA, Strenk SM, Fiedler TL, Hattangady N, Kowalsky J, Grady WM, Degli-Esposti MA, Varelias A, Clouston AD, van den Brink MRM, Dey N, Randolph TW, Markey KA, Fredricks DN, Hill GR. Koyama M, et al. Immunity. 2023 Aug 8;56(8):1876-1893.e8. doi: 10.1016/j.immuni.2023.06.024. Epub 2023 Jul 21. Immunity. 2023. PMID: 37480848 Free PMC article.
Microbiota dictate T cell clonal selection to augment graft-versus-host disease after stem cell transplantation.
Yeh AC, Koyama M, Waltner OG, Minnie SA, Boiko JR, Shabaneh TB, Takahashi S, Zhang P, Ensbey KS, Schmidt CR, Legg SRW, Sekiguchi T, Nelson E, Bhise SS, Stevens AR, Goodpaster T, Chakka S, Furlan SN, Markey KA, Bleakley ME, Elson CO, Bradley PH, Hill GR. Yeh AC, et al. Immunity. 2024 Jul 9;57(7):1648-1664.e9. doi: 10.1016/j.immuni.2024.05.018. Epub 2024 Jun 13. Immunity. 2024. PMID: 38876098
Calcineurin inhibition rescues alloantigen-specific central memory T cell subsets that promote chronic GVHD.
Wang Y, Ullah MA, Waltner OG, Bhise SS, Ensbey KS, Schmidt CR, Legg SR, Sekiguchi T, Nelson EL, Kuns RD, Nemychenkov NS, Atilla E, Yeh AC, Takahashi S, Boiko JR, Varelias A, Blazar BR, Koyama M, Minnie SA, Clouston AD, Furlan SN, Zhang P, Hill GR. Wang Y, et al. J Clin Invest. 2024 Jun 3;134(11):e170125. doi: 10.1172/JCI170125. J Clin Invest. 2024. PMID: 38828727 Free PMC article.
IFN-λ therapy prevents severe gastrointestinal graft-versus-host disease.
Henden AS, Koyama M, Robb RJ, Forero A, Kuns RD, Chang K, Ensbey KS, Varelias A, Kazakoff SH, Waddell N, Clouston AD, Giri R, Begun J, Blazar BR, Degli-Esposti MA, Kotenko SV, Lane SW, Bowerman KL, Savan R, Hugenholtz P, Gartlan KH, Hill GR. Henden AS, et al. Blood. 2021 Aug 26;138(8):722-737. doi: 10.1182/blood.2020006375. Blood. 2021. PMID: 34436524 Free PMC article.
13 results