R01 HL151447/HL/NHLBI NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2020	4
2021	3
2022	3
2023	1
2024	4
2025	1

1

Mitochondria as a primary determinant of angiogenic modality in pulmonary arterial hypertension.

Niihori M, James J, Varghese MV, McClain N, Lawal OS, Philip RC, Baggett BK, Goncharov DA, de Jesus Perez V, Goncharova EA, Rafikov R, Rafikova O. Niihori M, et al. J Exp Med. 2024 Nov 4;221(11):e20231568. doi: 10.1084/jem.20231568. Epub 2024 Sep 25. J Exp Med. 2024. PMID: 39320470 Free PMC article.

2

Single-cell and Spatial Transcriptomics Identified Fatty Acid-binding Proteins Controlling Endothelial Glycolytic and Arterial Programming in Pulmonary Hypertension.

Liu B, Yi D, Li S, Ramirez K, Xia X, Cao Y, Zhao H, Tripathi A, Qiu S, Kala M, Rafikov R, Gu H, de Jesus Perez V, Lemay SE, Glembotski CC, Knox KS, Bonnet S, Kalinichenko VV, Zhao YY, Fallon MB, Boucherat O, Dai Z. Liu B, et al. bioRxiv [Preprint]. 2024 Apr 15:2024.02.11.579846. doi: 10.1101/2024.02.11.579846. bioRxiv. 2024. Update in: Arterioscler Thromb Vasc Biol. 2025 Jul;45(7):1145-1165. doi: 10.1161/ATVBAHA.124.321173. PMID: 38370670 Free PMC article. Updated. Preprint.

3

Circulating free heme induces cytokine storm and pulmonary hypertension through the MKK3/p38 axis.

Valuparampil Varghese M, James J, Bharti D, Rischard F, Rafikova O, Rafikov R. Valuparampil Varghese M, et al. Am J Physiol Lung Cell Mol Physiol. 2024 Oct 1;327(4):L574-L586. doi: 10.1152/ajplung.00422.2022. Epub 2024 Aug 28. Am J Physiol Lung Cell Mol Physiol. 2024. PMID: 39197168 Free PMC article.

4

Cytokine profiling in pulmonary arterial hypertension: the role of redox homeostasis and sex.

Rafikov R, Rischard F, Vasilyev M, Varghese MV, Yuan JX, Desai AA, Garcia JGN, Rafikova O. Rafikov R, et al. Transl Res. 2022 Sep;247:1-18. doi: 10.1016/j.trsl.2022.03.013. Epub 2022 Apr 9. Transl Res. 2022. PMID: 35405322 Free PMC article.

5

Deciphering the Complexities of Pulmonary Hypertension: The Emergent Role of Single-Cell Omics.

Rafikov R, de Jesus Perez V, Dekan A, Kudryashova TV, Rafikova O. Rafikov R, et al. Am J Respir Cell Mol Biol. 2024 Aug 14;72(1):32-40. doi: 10.1165/rcmb.2024-0145PS. Online ahead of print. Am J Respir Cell Mol Biol. 2024. PMID: 39141563

6

Novel Populations of Lung Capillary Endothelial Cells and Their Functional Significance.

James J, Dekan A, Niihori M, McClain N, Varghese M, Bharti D, Lawal OS, Padilla-Rodrigez M, Yi D, Dai Z, Gusev O, Rafikova O, Rafikov R. James J, et al. Res Sq [Preprint]. 2023 May 3:rs.3.rs-2887159. doi: 10.21203/rs.3.rs-2887159/v1. Res Sq. 2023. PMID: 37205391 Free PMC article. Preprint.

7

Endothelial eNAMPT drives EndMT and preclinical PH: rescue by an eNAMPT-neutralizing mAb.

Ahmed M, Zaghloul N, Zimmerman P, Casanova NG, Sun X, Song JH, Hernon VR, Sammani S, Rischard F, Rafikova O, Rafikov R, Makino A, Kempf CL, Camp SM, Wang J, Desai AA, Lussier Y, Yuan JX, Garcia JGN. Ahmed M, et al. Pulm Circ. 2021 Nov 12;11(4):20458940211059712. doi: 10.1177/20458940211059712. eCollection 2021 Oct-Dec. Pulm Circ. 2021. PMID: 34790349 Free PMC article.

8

Glucose-6-phosphate dehydrogenase deficiency contributes to metabolic abnormality and pulmonary hypertension.

Varghese MV, James J, Rafikova O, Rafikov R. Varghese MV, et al. Am J Physiol Lung Cell Mol Physiol. 2021 Apr 1;320(4):L508-L521. doi: 10.1152/ajplung.00165.2020. Epub 2021 Jan 27. Am J Physiol Lung Cell Mol Physiol. 2021. PMID: 33502933 Free PMC article.

9

Heme induces rapid endothelial barrier dysfunction via the MKK3/p38MAPK axis.

James J, Srivastava A, Varghese MV, Eccles CA, Zemskova M, Rafikova O, Rafikov R. James J, et al. Blood. 2020 Aug 6;136(6):749-754. doi: 10.1182/blood.2019003986. Blood. 2020. PMID: 32548640 Free PMC article.

10

Single Mutation in the NFU1 Gene Metabolically Reprograms Pulmonary Artery Smooth Muscle Cells.

James J, Zemskova M, Eccles CA, Varghese MV, Niihori M, Barker NK, Luo M, Mandarino LJ, Langlais PR, Rafikova O, Rafikov R. James J, et al. Arterioscler Thromb Vasc Biol. 2021 Feb;41(2):734-754. doi: 10.1161/ATVBAHA.120.314655. Epub 2020 Dec 10. Arterioscler Thromb Vasc Biol. 2021. PMID: 33297749 Free PMC article.

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