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Structural basis of nucleosome-dependent cGAS inhibition.
Boyer JA, Spangler CJ, Strauss JD, Cesmat AP, Liu P, McGinty RK, Zhang Q. Boyer JA, et al. Science. 2020 Oct 23;370(6515):450-454. doi: 10.1126/science.abd0609. Epub 2020 Sep 10. Science. 2020. PMID: 32913000 Free PMC article.
MS0621, a novel small-molecule modulator of Ewing sarcoma chromatin accessibility, interacts with an RNA-associated macromolecular complex and influences RNA splicing.
Vital T, Wali A, Butler KV, Xiong Y, Foster JP 2nd, Marcel SS, McFadden AW, Nguyen VU, Bailey BM, Lamb KN, James LI, Frye SV, Mosely AL, Jin J, Pattenden SG, Davis IJ. Vital T, et al. Front Oncol. 2023 Jan 30;13:1099550. doi: 10.3389/fonc.2023.1099550. eCollection 2023. Front Oncol. 2023. PMID: 36793594 Free PMC article.