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Chromatin remodelling drives immune cell-fibroblast communication in heart failure.
Alexanian M, Padmanabhan A, Nishino T, Travers JG, Ye L, Pelonero A, Lee CY, Sadagopan N, Huang Y, Auclair K, Zhu A, An Y, Ekstrand CA, Martinez C, Teran BG, Flanigan WR, Kim CK, Lumbao-Conradson K, Gardner Z, Li L, Costa MW, Jain R, Charo I, Combes AJ, Haldar SM, Pollard KS, Vagnozzi RJ, McKinsey TA, Przytycki PF, Srivastava D. Alexanian M, et al. Nature. 2024 Nov;635(8038):434-443. doi: 10.1038/s41586-024-08085-6. Epub 2024 Oct 23. Nature. 2024. PMID: 39443808 Free PMC article.
A genome-wide CRISPR screen identifies BRD4 as a regulator of cardiomyocyte differentiation.
Padmanabhan A, de Soysa TY, Pelonero A, Sapp V, Shah PP, Wang Q, Li L, Lee CY, Sadagopan N, Nishino T, Ye L, Yang R, Karnay A, Poleshko A, Bolar N, Linares-Saldana R, Ranade SS, Alexanian M, Morton SU, Jain M, Haldar SM, Srivastava D, Jain R. Padmanabhan A, et al. Nat Cardiovasc Res. 2024 Mar;3(3):317-331. doi: 10.1038/s44161-024-00431-1. Epub 2024 Feb 23. Nat Cardiovasc Res. 2024. PMID: 39196112 Free PMC article.
The secret life of chromatin tethers.
Kiseleva AA, Poleshko A. Kiseleva AA, et al. FEBS Lett. 2023 Nov;597(22):2782-2790. doi: 10.1002/1873-3468.14685. Epub 2023 Jun 25. FEBS Lett. 2023. PMID: 37339933 Free PMC article. Review.
Chromatin Remodeling Drives Immune-Fibroblast Crosstalk in Heart Failure Pathogenesis.
Alexanian M, Padmanabhan A, Nishino T, Travers JG, Ye L, Lee CY, Sadagopan N, Huang Y, Pelonero A, Auclair K, Zhu A, Teran BG, Flanigan W, Kim CK, Lumbao-Conradson K, Costa M, Jain R, Charo I, Haldar SM, Pollard KS, Vagnozzi RJ, McKinsey TA, Przytycki PF, Srivastava D. Alexanian M, et al. bioRxiv [Preprint]. 2023 Jan 7:2023.01.06.522937. doi: 10.1101/2023.01.06.522937. bioRxiv. 2023. PMID: 36711864 Free PMC article. Preprint.
CTCF/RAD21 organize the ground state of chromatin-nuclear speckle association.
Yu R, Roseman S, Siegenfeld AP, Gardner Z, Nguyen SC, Tran KA, Joyce EF, Jain R, Liau BB, Krantz ID, Alexander KA, Berger SL. Yu R, et al. Nat Struct Mol Biol. 2025 Jun;32(6):1069-1080. doi: 10.1038/s41594-024-01465-6. Epub 2025 Feb 21. Nat Struct Mol Biol. 2025. PMID: 39984730 Free PMC article.