Cell height: Tao rising

J Cell Biol. 2012 Dec 24;199(7):1023-4. doi: 10.1083/jcb.201211015.

Abstract

During oogenesis in Drosophila melanogaster, the cells in the follicular epithelium of the ovary undergo a transition from a cuboidal to a squamous shape. In this issue, Gomez et al. (2012. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201207150) show that the kinase Tao promotes the endocytosis of the cell adhesion molecule Fasciclin 2 from the lateral surface of the cell and is critical for the cuboidal to squamous cell shape transition. Their results indicate that Tao is rising as a regulator of cell height.

Publication types

  • Research Support, N.I.H., Extramural
  • Comment

MeSH terms

  • Animals
  • Cell Adhesion Molecules, Neuronal / metabolism*
  • Cell Shape*
  • Drosophila Proteins / physiology*
  • Drosophila melanogaster / enzymology*
  • Endocytosis*
  • Epithelial Cells / physiology*
  • Female
  • Male
  • Protein Serine-Threonine Kinases / physiology*

Substances

  • Cell Adhesion Molecules, Neuronal
  • Drosophila Proteins
  • fasciclin II
  • Protein Serine-Threonine Kinases
  • Tao protein, Drosophila