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Glycolytic lactate in diabetic kidney disease.
Darshi M, Kugathasan L, Maity S, Sridhar VS, Fernandez R, Limonte CP, Grajeda BI, Saliba A, Zhang G, Drel VR, Kim JJ, Montellano R, Tumova J, Montemayor D, Wang Z, Liu JJ, Wang J, Perkins BA, Lytvyn Y, Natarajan L, Lim SC, Feldman H, Toto R, Sedor JR, Patel J, Waikar SS, Brown J, Osman Y, He J, Chen J, Reeves WB, de Boer IH, Roy S, Vallon V, Hallan S, Gelfond JA, Cherney DZ, Sharma K; Kidney Precision Medicine Project, and the CRIC Study Investigators. Darshi M, et al. JCI Insight. 2024 Jun 10;9(11):e168825. doi: 10.1172/jci.insight.168825. JCI Insight. 2024. PMID: 38855868 Free PMC article.
Endogenous adenine mediates kidney injury in diabetic models and predicts diabetic kidney disease in patients.
Sharma K, Zhang G, Hansen J, Bjornstad P, Lee HJ, Menon R, Hejazi L, Liu JJ, Franzone A, Looker HC, Choi BY, Fernandez R, Venkatachalam MA, Kugathasan L, Sridhar VS, Natarajan L, Zhang J, Sharma VS, Kwan B, Waikar SS, Himmelfarb J, Tuttle KR, Kestenbaum B, Fuhrer T, Feldman HI, de Boer IH, Tucci FC, Sedor J, Heerspink HL, Schaub J, Otto EA, Hodgin JB, Kretzler M, Anderton CR, Alexandrov T, Cherney D, Lim SC, Nelson RG, Gelfond J, Iyengar R; Kidney Precision Medicine Project. Sharma K, et al. J Clin Invest. 2023 Oct 16;133(20):e170341. doi: 10.1172/JCI170341. J Clin Invest. 2023. PMID: 37616058 Free PMC article.