R50 CA233186/CA/NCI NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2019	1
2020	8
2021	1
2024	3
2025	0

1

Clinically relevant orthotopic pancreatic cancer models for adoptive T cell transfer therapy.

Horvat NK, Karpovsky I, Phillips M, Wyatt MM, Hall MA, Herting CJ, Hammons J, Mahdi Z, Moffitt RA, Paulos CM, Lesinski GB. Horvat NK, et al. J Immunother Cancer. 2024 Jan 8;12(1):e008086. doi: 10.1136/jitc-2023-008086. J Immunother Cancer. 2024. PMID: 38191243 Free PMC article.

2

Progressively Enhancing Stemness of Adoptively Transferred T Cells with PI3Kδ Blockade Improves Metabolism and Antitumor Immunity.

Rangel Rivera GO, Dwyer CJ, Knochelmann HM, Smith AS, Aksoy BA, Cole AC, Wyatt MM, Kumaresan S, Thaxton JE, Lesinski GB, Paulos CM. Rangel Rivera GO, et al. Cancer Res. 2024 Jan 2;84(1):69-83. doi: 10.1158/0008-5472.CAN-23-0801. Cancer Res. 2024. PMID: 37801615 Free PMC article.

3

Tuft and Cancer Stem Cell Marker DCLK1: A New Target to Enhance Anti-Tumor Immunity in the Tumor Microenvironment.

Cao Z, Weygant N, Chandrakesan P, Houchen CW, Peng J, Qu D. Cao Z, et al. Cancers (Basel). 2020 Dec 17;12(12):3801. doi: 10.3390/cancers12123801. Cancers (Basel). 2020. PMID: 33348546 Free PMC article. Review.

4

Distinct host preconditioning regimens differentially impact the antitumor potency of adoptively transferred Th17 cells.

Wittling MC, Knochelmann HM, Wyatt MM, Rangel Rivera GO, Cole AC, Lesinski GB, Paulos CM. Wittling MC, et al. J Immunother Cancer. 2024 Jun 30;12(6):e008715. doi: 10.1136/jitc-2023-008715. J Immunother Cancer. 2024. PMID: 38945552 Free PMC article.

5

DCLK1-Isoform2 Alternative Splice Variant Promotes Pancreatic Tumor Immunosuppressive M2-Macrophage Polarization.

Chandrakesan P, Panneerselvam J, May R, Weygant N, Qu D, Berry WR, Pitts K, Stanger BZ, Rao CV, Bronze MS, Houchen CW. Chandrakesan P, et al. Mol Cancer Ther. 2020 Jul;19(7):1539-1549. doi: 10.1158/1535-7163.MCT-19-0776. Epub 2020 May 5. Mol Cancer Ther. 2020. PMID: 32371580 Free PMC article.

6

Cancer Stem Cell Marker DCLK1 Correlates with Tumorigenic Immune Infiltrates in the Colon and Gastric Adenocarcinoma Microenvironments.

Wu X, Qu D, Weygant N, Peng J, Houchen CW. Wu X, et al. Cancers (Basel). 2020 Jan 22;12(2):274. doi: 10.3390/cancers12020274. Cancers (Basel). 2020. PMID: 31979136 Free PMC article.

7

DCLK1 Regulates Tumor Stemness and Cisplatin Resistance in Non-small Cell Lung Cancer via ABCD-Member-4.

Panneerselvam J, Mohandoss P, Patel R, Gillan H, Li M, Kumar K, Nguyen D, Weygant N, Qu D, Pitts K, Lightfoot S, Rao C, Houchen C, Bronze M, Chandrakesan P. Panneerselvam J, et al. Mol Ther Oncolytics. 2020 May 27;18:24-36. doi: 10.1016/j.omto.2020.05.012. eCollection 2020 Sep 25. Mol Ther Oncolytics. 2020. PMID: 32637578 Free PMC article.

8

Doublecortin-like kinase 1 promotes hepatocyte clonogenicity and oncogenic programming via non-canonical β-catenin-dependent mechanism.

Ali N, Nguyen CB, Chandrakesan P, Wolf RF, Qu D, May R, Goretsky T, Fazili J, Barrett TA, Li M, Huycke MM, Bronze MS, Houchen CW. Ali N, et al. Sci Rep. 2020 Jun 29;10(1):10578. doi: 10.1038/s41598-020-67401-y. Sci Rep. 2020. PMID: 32601309 Free PMC article.

9

IL6 Fuels Durable Memory for Th17 Cell-Mediated Responses to Tumors.

Knochelmann HM, Dwyer CJ, Smith AS, Bowers JS, Wyatt MM, Nelson MH, Rangel Rivera GO, Horton JD, Krieg C, Armeson K, Lesinski GB, Rubinstein MP, Li Z, Paulos CM. Knochelmann HM, et al. Cancer Res. 2020 Sep 15;80(18):3920-3932. doi: 10.1158/0008-5472.CAN-19-3685. Epub 2020 Jun 19. Cancer Res. 2020. PMID: 32561531 Free PMC article.

10

Overexpression of DCLK1-AL Increases Tumor Cell Invasion, Drug Resistance, and KRAS Activation and Can Be Targeted to Inhibit Tumorigenesis in Pancreatic Cancer.

Qu D, Weygant N, Yao J, Chandrakesan P, Berry WL, May R, Pitts K, Husain S, Lightfoot S, Li M, Wang TC, An G, Clendenin C, Stanger BZ, Houchen CW. Qu D, et al. J Oncol. 2019 Aug 5;2019:6402925. doi: 10.1155/2019/6402925. eCollection 2019. J Oncol. 2019. PMID: 31467540 Free PMC article.

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