Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2022 1
2023 4
2024 12
2025 3

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

20 results

Results by year

Filters applied: . Clear all
Page 1
Relocalizing transcriptional kinases to activate apoptosis.
Sarott RC, Gourisankar S, Karim B, Nettles S, Yang H, Dwyer BG, Simanauskaite JM, Tse J, Abuzaid H, Krokhotin A, Zhang T, Hinshaw SM, Green MR, Crabtree GR, Gray NS. Sarott RC, et al. Science. 2024 Oct 4;386(6717):eadl5361. doi: 10.1126/science.adl5361. Epub 2024 Oct 4. Science. 2024. PMID: 39361741
Targeting colorectal cancer with small-molecule inhibitors of ALDH1B1.
Feng Z, Hom ME, Bearrood TE, Rosenthal ZC, Fernández D, Ondrus AE, Gu Y, McCormick AK, Tomaske MG, Marshall CR, Kline T, Chen CH, Mochly-Rosen D, Kuo CJ, Chen JK. Feng Z, et al. Nat Chem Biol. 2022 Oct;18(10):1065-1075. doi: 10.1038/s41589-022-01048-w. Epub 2022 Jul 4. Nat Chem Biol. 2022. PMID: 35788181 Free PMC article.
Template-assisted covalent modification underlies activity of covalent molecular glues.
Li YD, Ma MW, Hassan MM, Hunkeler M, Teng M, Puvar K, Rutter JC, Lumpkin RJ, Sandoval B, Jin CY, Schmoker AM, Ficarro SB, Cheong H, Metivier RJ, Wang MY, Xu S, Byun WS, Groendyke BJ, You I, Sigua LH, Tavares I, Zou C, Tsai JM, Park PMC, Yoon H, Majewski FC, Sperling HT, Marto JA, Qi J, Nowak RP, Donovan KA, Słabicki M, Gray NS, Fischer ES, Ebert BL. Li YD, et al. Nat Chem Biol. 2024 Dec;20(12):1640-1649. doi: 10.1038/s41589-024-01668-4. Epub 2024 Jul 29. Nat Chem Biol. 2024. PMID: 39075252 Free PMC article.
Discovery of electrophilic degraders that exploit SNAr chemistry.
Zhuang Z, Byun WS, Kozicka Z, Dwyer BG, Donovan KA, Jiang Z, Jones HM, Abeja DM, Nix MN, Zhong J, Słabicki M, Fischer ES, Ebert BL, Gray NS. Zhuang Z, et al. bioRxiv [Preprint]. 2024 Sep 27:2024.09.25.615094. doi: 10.1101/2024.09.25.615094. bioRxiv. 2024. PMID: 39386645 Free PMC article. Preprint.
Activating p53Y220C with a Mutant-Specific Small Molecule.
Zhu X, Byun WS, Pieńkowska DE, Nguyen KT, Gerhartz J, Geng Q, Qiu T, Zhong J, Jiang Z, Wang M, Sarott RC, Hinshaw SM, Zhang T, Attardi LD, Nowak RP, Gray NS. Zhu X, et al. bioRxiv [Preprint]. 2024 Oct 28:2024.10.23.619961. doi: 10.1101/2024.10.23.619961. bioRxiv. 2024. PMID: 39554093 Free PMC article. Preprint.
A Bivalent Molecular Glue Linking Lysine Acetyltransferases to Oncogene-induced Cell Death.
Nix MN, Gourisankar S, Sarott RC, Dwyer BG, Nettles SA, Martinez MM, Abuzaid H, Yang H, Wang Y, Simanauskaite JM, Romero BA, Jones HM, Krokhotin A, Lowensohn TN, Chen L, Low C, Davis MM, Fernandez D, Zhang T, Green MR, Hinshaw SM, Gray NS, Crabtree GR. Nix MN, et al. bioRxiv [Preprint]. 2025 Mar 17:2025.03.14.643404. doi: 10.1101/2025.03.14.643404. bioRxiv. 2025. PMID: 40166243 Free PMC article. Preprint.
Exploration of the tunability of BRD4 degradation by DCAF16 trans-labelling covalent glues.
Hassan MM, Li YD, Ma MW, Teng M, Byun WS, Puvar K, Lumpkin R, Sandoval B, Rutter JC, Jin CY, Wang MY, Xu S, Schmoker AM, Cheong H, Groendyke BJ, Qi J, Fischer ES, Ebert BL, Gray NS. Hassan MM, et al. Eur J Med Chem. 2024 Dec 5;279:116904. doi: 10.1016/j.ejmech.2024.116904. Epub 2024 Sep 24. Eur J Med Chem. 2024. PMID: 39341093 Free PMC article.
20 results