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Avidity and variable domain spacing strongly influence the therapeutic potency of bispecific antibodies against Crimean-Congo hemorrhagic fever virus.
Wang A, Monticelli SR, Wirchnianski AS, Abelson DM, Kuehne AI, Bakken RR, Middlecamp M, Weingart M, Vergnolle O, Bornholdt ZA, Moyer CL, Berrigan JL, West BR, Fels JM, Zeitlin L, Herbert AS, Chandran K, Bikash CR, Lai JR. Wang A, et al. mBio. 2025 May 14;16(5):e0320224. doi: 10.1128/mbio.03202-24. Epub 2025 Apr 16. mBio. 2025. PMID: 40237506 Free PMC article.