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Farnesoid X nuclear receptor ligand obeticholic acid for non-cirrhotic, non-alcoholic steatohepatitis (FLINT): a multicentre, randomised, placebo-controlled trial.
Neuschwander-Tetri BA, Loomba R, Sanyal AJ, Lavine JE, Van Natta ML, Abdelmalek MF, Chalasani N, Dasarathy S, Diehl AM, Hameed B, Kowdley KV, McCullough A, Terrault N, Clark JM, Tonascia J, Brunt EM, Kleiner DE, Doo E; NASH Clinical Research Network. Neuschwander-Tetri BA, et al. Lancet. 2015 Mar 14;385(9972):956-65. doi: 10.1016/S0140-6736(14)61933-4. Epub 2014 Nov 7. Lancet. 2015. PMID: 25468160 Free PMC article. Clinical Trial.
MASLD in people with HIV exhibits higher fibrosis stage despite lower disease activity than in matched controls.
Allende DS, Cummings O, Sternberg AL, Behling CA, Carpenter D, Gill RM, Guy CD, Yeh MM, Gawrieh S, Sterling RK, Naggie S, Loomba R, Price JC, McLaughlin M, Hadigan C, Crandall H, Belt P, Wilson L, Chalasani NP, Kleiner DE; HIV NASH and NASH Clinical Research Groups. Allende DS, et al. Aliment Pharmacol Ther. 2024 Nov;60(10):1351-1360. doi: 10.1111/apt.18236. Epub 2024 Sep 5. Aliment Pharmacol Ther. 2024. PMID: 39238213
Magnetic resonance elastography biomarkers for detection of histologic alterations in nonalcoholic fatty liver disease in the absence of fibrosis.
Qu Y, Middleton MS, Loomba R, Glaser KJ, Chen J, Hooker JC, Wolfson T, Covarrubias Y, Valasek MA, Fowler KJ, Zhang YN, Sy E, Gamst AC, Wang K, Mamidipalli A, Schwimmer JB, Song B, Reeder SB, Yin M, Ehman RL, Sirlin CB. Qu Y, et al. Eur Radiol. 2021 Nov;31(11):8408-8419. doi: 10.1007/s00330-021-07988-6. Epub 2021 Apr 26. Eur Radiol. 2021. PMID: 33899143 Free PMC article.
42 results