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Page 1
Systems-based identification of the Hippo pathway for promoting fibrotic mesenchymal differentiation in systemic sclerosis.
Ma F, Tsou PS, Gharaee-Kermani M, Plazyo O, Xing X, Kirma J, Wasikowski R, Hile GA, Harms PW, Jiang Y, Xing E, Nakamura M, Ochocki D, Brodie WD, Pillai S, Maverakis E, Pellegrini M, Modlin RL, Varga J, Tsoi LC, Lafyatis R, Kahlenberg JM, Billi AC, Khanna D, Gudjonsson JE. Ma F, et al. Nat Commun. 2024 Jan 3;15(1):210. doi: 10.1038/s41467-023-44645-6. Nat Commun. 2024. PMID: 38172207 Free PMC article.
An agonistic anti-signal regulatory protein α antibody for chronic inflammatory diseases.
Xie MM, Dai B, Hackney JA, Sun T, Zhang J, Jackman JK, Jeet S, Irizarry-Caro RA, Fu Y, Liang Y, Bender H, Shamir ER, Keir ME, Bevers J, Nakamura G, Townsend MJ, Fox DA, Scherl A, Lee WP, Martin F, Godowski PJ, Pappu R, Yi T. Xie MM, et al. Cell Rep Med. 2023 Aug 15;4(8):101130. doi: 10.1016/j.xcrm.2023.101130. Epub 2023 Jul 24. Cell Rep Med. 2023. PMID: 37490914 Free PMC article.
CD6 is a target for cancer immunotherapy.
Ruth JH, Gurrea-Rubio M, Athukorala KS, Rasmussen SM, Weber DP, Randon PM, Gedert RJ, Lind ME, Amin MA, Campbell PL, Tsou PS, Mao-Draayer Y, Wu Q, Lanigan TM, Keshamouni VG, Singer NG, Lin F, Fox DA. Ruth JH, et al. JCI Insight. 2021 Mar 8;6(5):e145662. doi: 10.1172/jci.insight.145662. JCI Insight. 2021. PMID: 33497367 Free PMC article.
Targeting CD13/Aminopeptidase N as a Novel Therapeutic Approach for Scleroderma Fibrosis.
Muraoka S, Brodie WD, Mattichak MN, Gurrea-Rubio M, Ikari Y, Foster C, Amin MA, Khanna N, Amin H, Campbell PL, Vichaikul S, Model EN, Omara MM, Petrovski S, Kozicki K, Amarista C, Webber A, Ali M, Palisoc PJ, Hervoso J, Ruth JH, Tsoi LC, Varga J, Gudjonsson JE, Khanna D, Fox DA, Tsou PS. Muraoka S, et al. Arthritis Rheumatol. 2025 Jan;77(1):80-91. doi: 10.1002/art.42973. Epub 2024 Sep 18. Arthritis Rheumatol. 2025. PMID: 39175116 Free article.
Activation of cytotoxic lymphocytes through CD6 enhances killing of cancer cells.
Gurrea-Rubio M, Wu Q, Amin MA, Tsou PS, Campbell PL, Amarista CI, Ikari Y, Brodie WD, Mattichak MN, Muraoka S, Randon PM, Lind ME, Ruth JH, Mao-Draayer Y, Ding S, Shen X, Cooney LA, Lin F, Fox DA. Gurrea-Rubio M, et al. Cancer Immunol Immunother. 2024 Jan 27;73(2):34. doi: 10.1007/s00262-023-03578-1. Cancer Immunol Immunother. 2024. PMID: 38280067 Free PMC article.
49 results