Y01 GM000080/GM/NIGMS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2006	3
2007	5
2008	9
2009	12
2010	7
2011	10
2012	11
2013	7
2014	8
2015	11
2016	4
2017	3
2018	1
2019	3
2023	1
2024	2
2025	0

1

A highly stable prefusion RSV F vaccine derived from structural analysis of the fusion mechanism.

Krarup A, Truan D, Furmanova-Hollenstein P, Bogaert L, Bouchier P, Bisschop IJM, Widjojoatmodjo MN, Zahn R, Schuitemaker H, McLellan JS, Langedijk JPM. Krarup A, et al. Nat Commun. 2015 Sep 3;6:8143. doi: 10.1038/ncomms9143. Nat Commun. 2015. PMID: 26333350 Free PMC article.

2

Human CD4-binding site antibody elicited by polyvalent DNA prime-protein boost vaccine neutralizes cross-clade tier-2-HIV strains.

Wang S, Chan KW, Wei D, Ma X, Liu S, Hu G, Park S, Pan R, Gu Y, Nazzari AF, Olia AS, Xu K, Lin BC, Louder MK, McKee K, Doria-Rose NA, Montefiori D, Seaman MS, Zhou T, Kwong PD, Arthos J, Kong XP, Lu S. Wang S, et al. Nat Commun. 2024 May 21;15(1):4301. doi: 10.1038/s41467-024-48514-8. Nat Commun. 2024. PMID: 38773089 Free PMC article.

3

Mechanism of IRSp53 inhibition by 14-3-3.

Kast DJ, Dominguez R. Kast DJ, et al. Nat Commun. 2019 Jan 29;10(1):483. doi: 10.1038/s41467-019-08317-8. Nat Commun. 2019. PMID: 30696821 Free PMC article.

4

Catalytic mechanism of human alpha-galactosidase.

Guce AI, Clark NE, Salgado EN, Ivanen DR, Kulminskaya AA, Brumer H 3rd, Garman SC. Guce AI, et al. J Biol Chem. 2010 Feb 5;285(6):3625-3632. doi: 10.1074/jbc.M109.060145. Epub 2009 Nov 25. J Biol Chem. 2010. PMID: 19940122 Free PMC article.

5

Pharmacological chaperones for human α-N-acetylgalactosaminidase.

Clark NE, Metcalf MC, Best D, Fleet GW, Garman SC. Clark NE, et al. Proc Natl Acad Sci U S A. 2012 Oct 23;109(43):17400-5. doi: 10.1073/pnas.1203924109. Epub 2012 Oct 8. Proc Natl Acad Sci U S A. 2012. PMID: 23045655 Free PMC article.

6

Zinc-mediated allosteric inhibition of caspase-6.

Velázquez-Delgado EM, Hardy JA. Velázquez-Delgado EM, et al. J Biol Chem. 2012 Oct 19;287(43):36000-11. doi: 10.1074/jbc.M112.397752. Epub 2012 Aug 13. J Biol Chem. 2012. PMID: 22891250 Free PMC article.

7

Mechanism of actin filament pointed-end capping by tropomodulin.

Rao JN, Madasu Y, Dominguez R. Rao JN, et al. Science. 2014 Jul 25;345(6195):463-7. doi: 10.1126/science.1256159. Science. 2014. PMID: 25061212 Free PMC article.

8

Allosteric inhibition of the NS2B-NS3 protease from dengue virus.

Yildiz M, Ghosh S, Bell JA, Sherman W, Hardy JA. Yildiz M, et al. ACS Chem Biol. 2013 Dec 20;8(12):2744-52. doi: 10.1021/cb400612h. Epub 2013 Oct 28. ACS Chem Biol. 2013. PMID: 24164286 Free PMC article.

9

Substrate-induced conformational changes occur in all cleaved forms of caspase-6.

Vaidya S, Velázquez-Delgado EM, Abbruzzese G, Hardy JA. Vaidya S, et al. J Mol Biol. 2011 Feb 11;406(1):75-91. doi: 10.1016/j.jmb.2010.11.031. Epub 2010 Nov 25. J Mol Biol. 2011. PMID: 21111746 Free PMC article.

10

Loss of a Functionally and Structurally Distinct ld-Transpeptidase, LdtMt5, Compromises Cell Wall Integrity in Mycobacterium tuberculosis.

Brammer Basta LA, Ghosh A, Pan Y, Jakoncic J, Lloyd EP, Townsend CA, Lamichhane G, Bianchet MA. Brammer Basta LA, et al. J Biol Chem. 2015 Oct 16;290(42):25670-85. doi: 10.1074/jbc.M115.660753. Epub 2015 Aug 24. J Biol Chem. 2015. PMID: 26304120 Free PMC article.

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