ACP Journal Club Editorial Team at McMaster University[Corporate Author] - Search Results

1

In adults with obesity and knee OA, adding weekly semaglutide to diet and activity counseling reduced weight and knee pain at 68 wk.

Bell DSH; ACP Journal Club Editorial Team at McMaster University. Bell DSH, et al. Ann Intern Med. 2025 Feb;178(2):JC20. doi: 10.7326/ANNALS-24-03988-JC. Epub 2025 Feb 4. Ann Intern Med. 2025. PMID: 39899871

2

In HFpEF, semaglutide reduced a composite of worsening HF or CV death.

Lam SHM, Lip GYH; ACP Journal Club Editorial Team at McMaster University. Lam SHM, et al. Ann Intern Med. 2025 Jan;178(1):JC4. doi: 10.7326/ANNALS-24-03382-JC. Epub 2025 Jan 7. Ann Intern Med. 2025. PMID: 39761583

3

In severe asthma with an eosinophilic phenotype, depemokimab improved exacerbations, but not quality of life, at 52 wk.

McDonald CF; ACP Journal Club Editorial Team at McMaster University. McDonald CF, et al. Ann Intern Med. 2025 Jan;178(1):JC8. doi: 10.7326/ANNALS-24-03437-JC. Epub 2025 Jan 7. Ann Intern Med. 2025. PMID: 39761576

4

In HF with mildly reduced or preserved ejection fraction, finerenone reduced worsening HF or CV death at 32 mo.

Chitsazan M, Van Spall HGC; ACP Journal Club Editorial Team at McMaster University. Chitsazan M, et al. Ann Intern Med. 2025 Jan;178(1):JC2. doi: 10.7326/ANNALS-24-03365-JC. Epub 2025 Jan 7. Ann Intern Med. 2025. PMID: 39761584

5

In T1D, weekly efsitora was noninferior to daily degludec for reducing HbA_1c but increased severe hypoglycemia at 26 wk.

Larios F, Gionfriddo MR, Montori VM; ACP Journal Club Editorial Team at McMaster University. Larios F, et al. Ann Intern Med. 2025 Jan;178(1):JC11. doi: 10.7326/ANNALS-24-03440-JC. Epub 2025 Jan 7. Ann Intern Med. 2025. PMID: 39761586

6

In subclinical AF, apixaban vs. aspirin reduced stroke or systemic embolism at 3.5 y, regardless of duration of recent subclinical AF episodes.

Bates ER; ACP Journal Club Editorial Team at McMaster University. Bates ER, et al. Ann Intern Med. 2025 Jan;178(1):JC7. doi: 10.7326/ANNALS-24-03370-JC. Epub 2025 Jan 7. Ann Intern Med. 2025. PMID: 39761588

7

In adults with HF with preserved ejection fraction and obesity, tirzepatide reduced a composite of CV death or worsening HF at 2 y.

Ynalvez LA, Deswal A; ACP Journal Club Editorial Team at McMaster University. Ynalvez LA, et al. Ann Intern Med. 2025 Apr;178(4):JC43. doi: 10.7326/ANNALS-25-00468-JC. Epub 2025 Apr 1. Ann Intern Med. 2025. PMID: 40163881

8

CBT and rehabilitation improved long COVID symptoms.

Granwehr BP; ACP Journal Club Editorial Team at McMaster University. Granwehr BP, et al. Ann Intern Med. 2025 Mar;178(3):JC28. doi: 10.7326/ANNALS-25-00369-JC. Epub 2025 Mar 4. Ann Intern Med. 2025. PMID: 40030181

9

Guideline recommends antiviral prophylaxis for patients at high risk for HBV reactivation.

Pirzada SA, Sherker AH; ACP Journal Club Editorial Team at McMaster University. Pirzada SA, et al. Ann Intern Med. 2025 May;178(5):JC50. doi: 10.7326/ANNALS-25-01453-JC. Epub 2025 May 6. Ann Intern Med. 2025. PMID: 40324189

10

In nonseasonal depressive disorders, bright light therapy improves response and remission rates.

Leung LB; ACP Journal Club Editorial Team at McMaster University. Leung LB, et al. Ann Intern Med. 2025 Feb;178(2):JC21. doi: 10.7326/ANNALS-24-03833-JC. Epub 2025 Feb 4. Ann Intern Med. 2025. PMID: 39899860

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