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Serum aryl hydrocarbon receptor activity is associated with survival in patients with alcohol-associated hepatitis.
Yamazaki T, Kouno T, Hsu CL, Hartmann P, Mayo S, Zhang X, Stärkel P, Bosques-Padilla F, Verna EC, Abraldes JG, Brown RS Jr, Vargas V, Altamirano J, Caballería J, Shawcross DL, Louvet A, Lucey MR, Mathurin P, Garcia-Tsao G, Bataller R, Schnabl B; AlcHepNet Investigators. Yamazaki T, et al. Hepatology. 2024 Aug 1;80(2):403-417. doi: 10.1097/HEP.0000000000000777. Epub 2024 Feb 20. Hepatology. 2024. PMID: 38377466
Randomized trial of anakinra plus zinc vs. prednisone for severe alcohol-associated hepatitis.
Gawrieh S, Dasarathy S, Tu W, Kamath PS, Chalasani NP, McClain CJ, Bataller R, Szabo G, Tang Q, Radaeva S, Barton B, Nagy LE, Shah VH, Sanyal AJ, Mitchell MC; AlcHepNet Investigators. Gawrieh S, et al. J Hepatol. 2024 May;80(5):684-693. doi: 10.1016/j.jhep.2024.01.031. Epub 2024 Feb 10. J Hepatol. 2024. PMID: 38342441 Free PMC article. Clinical Trial.
Acute kidney injury in severe alcohol-associated hepatitis treated with anakinra plus zinc or prednisone.
Patidar KR, Tu W, Cotter TG, Simonetto DA, Asgharpour A, Jan MY, Tang Q, Yu Y, Li Y, Taiwo M, Thevkar Nagesh P, Dasarathy S, Kamath PS, McClain CJ, Chalasani N, Szabo G, Bataller R, Mitchell M, Mehal WZ, Nagy LE, Shah VH, Gawrieh S, Sanyal AJ; AlcHepNet Investigators. Patidar KR, et al. Hepatology. 2025 Apr 1;81(4):1256-1268. doi: 10.1097/HEP.0000000000001019. Epub 2024 Jul 19. Hepatology. 2025. PMID: 39028887 Clinical Trial.
Design of a multicenter randomized clinical trial for treatment of Alcohol-Associated Hepatitis.
Tu W, Gawrieh S, Dasarathy S, Mitchell MC, Simonetto DA, Patidar KR, McClain CJ, Bataller R, Szabo G, Tang Q, Barton BA, Radaeva S, Sanyal AJ, Shah V; Alcoholic Hepatitis Network (AlcHepNet) Investigators. Tu W, et al. Contemp Clin Trials Commun. 2023 Jan 18;32:101074. doi: 10.1016/j.conctc.2023.101074. eCollection 2023 Apr. Contemp Clin Trials Commun. 2023. PMID: 36698742 Free PMC article.
Parental liver disease mortality is associated with unfavorable outcomes in patients with alcohol-associated hepatitis.
Tu W, Gawrieh S, Nephew L, McClain C, Tang Q, Dasarathy S, Vatsalya V, Simonetto DA, Kettler C, Szabo G, Barton B, Yu Y, Kamath PS, Sanyal AJ, Nagy L, Mitchell MC, Liangpunsakul S, Shah VH, Chalasani N, Bataller R; AlcHepNet Investigators. Tu W, et al. Hepatol Commun. 2025 May 23;9(6):e0666. doi: 10.1097/HC9.0000000000000666. eCollection 2025 Jun 1. Hepatol Commun. 2025. PMID: 40408279 Free PMC article.