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Page 1
Intravenous tenecteplase compared with alteplase for acute ischaemic stroke in Canada (AcT): a pragmatic, multicentre, open-label, registry-linked, randomised, controlled, non-inferiority trial.
Menon BK, Buck BH, Singh N, Deschaintre Y, Almekhlafi MA, Coutts SB, Thirunavukkarasu S, Khosravani H, Appireddy R, Moreau F, Gubitz G, Tkach A, Catanese L, Dowlatshahi D, Medvedev G, Mandzia J, Pikula A, Shankar J, Williams H, Field TS, Manosalva A, Siddiqui M, Zafar A, Imoukhuede O, Hunter G, Demchuk AM, Mishra S, Gioia LC, Jalini S, Cayer C, Phillips S, Elamin E, Shoamanesh A, Subramaniam S, Kate M, Jacquin G, Camden MC, Benali F, Alhabli I, Bala F, Horn M, Stotts G, Hill MD, Gladstone DJ, Poppe A, Sehgal A, Zhang Q, Lethebe BC, Doram C, Ademola A, Shamy M, Kenney C, Sajobi TT, Swartz RH; AcT Trial Investigators. Menon BK, et al. Among authors: appireddy r. Lancet. 2022 Jul 16;400(10347):161-169. doi: 10.1016/S0140-6736(22)01054-6. Epub 2022 Jun 29. Lancet. 2022. PMID: 35779553 Clinical Trial.
Tenecteplase versus standard of care for minor ischaemic stroke with proven occlusion (TEMPO-2): a randomised, open label, phase 3 superiority trial.
Coutts SB, Ankolekar S, Appireddy R, Arenillas JF, Assis Z, Bailey P, Barber PA, Bazan R, Buck BH, Butcher KS, Camden MC, Campbell BCV, Casaubon LK, Catanese L, Chatterjee K, Choi PMC, Clarke B, Dowlatshahi D, Ferrari J, Field TS, Ganesh A, Ghia D, Goyal M, Greisenegger S, Halse O, Horn M, Hunter G, Imoukhuede O, Kelly PJ, Kennedy J, Kenney C, Kleinig TJ, Krishnan K, Lima F, Mandzia JL, Marko M, Martins SO, Medvedev G, Menon BK, Mishra SM, Molina C, Moussaddy A, Muir KW, Parsons MW, Penn AMW, Pille A, Pontes-Neto OM, Roffe C, Serena J, Simister R, Singh N, Spratt N, Strbian D, Tham CH, Wiggam MI, Williams DJ, Willmot MR, Wu T, Yu AYX, Zachariah G, Zafar A, Zerna C, Hill MD; TEMPO-2 investigators. Coutts SB, et al. Among authors: appireddy r. Lancet. 2024 Jun 15;403(10444):2597-2605. doi: 10.1016/S0140-6736(24)00921-8. Epub 2024 May 17. Lancet. 2024. PMID: 38768626 Clinical Trial.
Safety and Efficacy of Tenecteplase Compared With Alteplase in Patients With Large Vessel Occlusion Stroke: A Prespecified Secondary Analysis of the ACT Randomized Clinical Trial.
Bala F, Singh N, Buck B, Ademola A, Coutts SB, Deschaintre Y, Khosravani H, Appireddy R, Moreau F, Phillips S, Gubitz G, Tkach A, Catanese L, Dowlatshahi D, Medvedev G, Mandzia J, Pikula A, Shankar JJ, Williams H, Field TS, Manosalva Alzate A, Siddiqui M, Zafar A, Imoukhoude O, Hunter G, Alhabli I, Benali F, Horn M, Hill MD, Shamy M, Sajobi TT, Swartz RH, Menon BK, Almekhlafi M. Bala F, et al. Among authors: appireddy r. JAMA Neurol. 2023 Aug 1;80(8):824-832. doi: 10.1001/jamaneurol.2023.2094. JAMA Neurol. 2023. PMID: 37428494 Free PMC article. Clinical Trial.
A Randomized Controlled Trial of Tenecteplase Versus Standard of Care for Minor Ischemic Stroke with Proven Occlusion (TEMPO-2): Rational and design of a multicenter, randomized open-label clinical trial.
Singh N, Kenney CC, Butcher KS, Buck B, Barber PA, Field TS, Choi PM, Yu AY, Kleinig T, Appireddy R, Molina CA, Muir KW, Hill MD, Coutts SB. Singh N, et al. Among authors: appireddy r. Int J Stroke. 2024 Aug;19(7):817-822. doi: 10.1177/17474930241253702. Epub 2024 May 17. Int J Stroke. 2024. PMID: 38676572 Free PMC article.
Effect of Time to Thrombolysis on Clinical Outcomes in Patients With Acute Ischemic Stroke Treated With Tenecteplase Compared to Alteplase: Analysis From the AcT Randomized Controlled Trial.
Singh N, Almekhlafi MA, Bala F, Ademola A, Coutts SB, Deschaintre Y, Khosravani H, Buck B, Appireddy R, Moreau F, Gubitz G, Tkach A, Catanese L, Dowlatshahi D, Medvedev G, Mandzia J, Pikula A, Shankar JJ, Ghrooda E, Poppe AY, Williams H, Field TS, Manosalva A, Siddiqui MM, Zafar A, Imoukhoude O, Hunter G, Shamy M, Demchuk AM, Claggett BL, Hill MD, Sajobi TT, Swartz RH, Menon BK. Singh N, et al. Among authors: appireddy r. Stroke. 2023 Nov;54(11):2766-2775. doi: 10.1161/STROKEAHA.123.044267. Epub 2023 Oct 6. Stroke. 2023. PMID: 37800372 Clinical Trial.
Surgery for Moyamoya Disease in Children.
Appireddy R, Ranjan M, Durafourt BA, Riva-Cambrin J, Hader WJ, Adelson PD. Appireddy R, et al. J Child Neurol. 2019 Aug;34(9):517-529. doi: 10.1177/0883073819844854. Epub 2019 May 8. J Child Neurol. 2019. PMID: 31066331 Review.
Imaging in acute stroke.
Eswaradass P, Appireddy R, Evans J, Tham C, Dey S, Najm M, Menon BK. Eswaradass P, et al. Among authors: appireddy r. Expert Rev Cardiovasc Ther. 2016 Aug;14(8):963-75. doi: 10.1080/14779072.2016.1196134. Epub 2016 Jun 16. Expert Rev Cardiovasc Ther. 2016. PMID: 27249030 Review.
Intravenous alteplase versus tenecteplase in patients with acute posterior circulation strokes: A secondary analysis from the AcT randomized controlled trial.
Cimflova P, Alhabli I, Bala F, Horn M, Benali F, Buck BH, Catanese L, Coutts PSB, Khosravani H, Appireddy R, Tkach A, Dowlatshahi D, Carpani F, Field T, Hunter G, Hill PMD, Poppe AY, Ademola A, Shamy M, Sajobi TT, Swartz RH, Almekhlafi MA, Menon PBK, Singh N. Cimflova P, et al. Among authors: appireddy r. J Stroke Cerebrovasc Dis. 2024 Nov;33(11):107985. doi: 10.1016/j.jstrokecerebrovasdis.2024.107985. Epub 2024 Aug 31. J Stroke Cerebrovasc Dis. 2024. PMID: 39222700 Clinical Trial.
Combination Antithrombotic Therapy for Reduction of Recurrent Ischemic Stroke in Intracranial Atherosclerotic Disease.
Perera KS, Sharma MA, Eikelboom JW, Ng KKH, Field TS, Buck BH, Hill MD, Stotts G, Casaubon LK, Mandzia J, Katsanos AH, Yip S, Shoamanesh A, Young GB, Appireddy R, Nayar S, Swartz R, Taylor A, Carrier A, Srivastava A, Deshmukh AS, Zhao R, Hart RG; CATIS-ICAD Investigators. Perera KS, et al. Among authors: appireddy r. Stroke. 2025 Feb;56(2):380-389. doi: 10.1161/STROKEAHA.124.047715. Epub 2025 Jan 9. Stroke. 2025. PMID: 39781748 Clinical Trial.
Virtual Care for Neurological Practice.
Appireddy R, Bendahan N, Chaitanya J, Shukla G. Appireddy R, et al. Ann Indian Acad Neurol. 2020 Sep-Oct;23(5):587-591. doi: 10.4103/aian.AIAN_415_20. Epub 2020 Dec 8. Ann Indian Acad Neurol. 2020. PMID: 33623255 Free PMC article.
49 results