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Test of Rapamycin in Aging Dogs (TRIAD): study design and rationale for a prospective, parallel-group, double-masked, randomized, placebo-controlled, multicenter trial of rapamycin in healthy middle-aged dogs from the Dog Aging Project.
Coleman AE, Creevy KE, Anderson R, Reed MJ, Fajt VR, Aicher KM, Atiee G, Barnett BG, Baumwart RD, Boudreau B, Cunningham SM, Dunbar MD, Ditzler B, Ferguson AM, Forsyth KK, Gambino AN, Gordon SG, Hammond HK, Holland SN, Iannaccone MK, Illing K, Kadotani S, Knowles SA, MacLean EL, Maran BA, Markovic LE, McGrath S, Melvin RL, Mueller MS, Nelson OL, Olby NJ, Pancotto TE, Parsley E, Potter BM, Prescott JO, Saunders AB, Sawyer HM, Scansen BA, Schmid SM, Smith CC, Tjostheim SS, Tolbert MK, Tropf MA, Visser LC, Ward JL, Wesselowski SR, Windsor RC, Yang VK, Ruple A, Promislow DEL, Kaeberlein M; Dog Aging Project Consortium. Coleman AE, et al. Geroscience. 2025 Jun;47(3):2851-2877. doi: 10.1007/s11357-024-01484-7. Epub 2025 Feb 14. Geroscience. 2025. PMID: 39951177 Free PMC article. Review.
Characterizing dog cognitive aging using spontaneous problem-solving measures: development of a battery of tests from the Dog Aging Project.
Hargrave SH, Bray EE, McGrath S, Alexander GE, Block TA, Chao N, Darvas M, Douglas LELC, Galante J, Kennedy BS, Kusick B, Moreno JA, Promislow DEL, Raichlen DA, Switzer LR, Tees L, Underwood Aguilar M, Urfer SR; Dog Aging Project Consortium; MacLean EL. Hargrave SH, et al. Geroscience. 2025 Feb;47(1):23-43. doi: 10.1007/s11357-024-01278-x. Epub 2024 Aug 6. Geroscience. 2025. PMID: 39106023 Free PMC article.
31 results