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Permissive central tolerance plus defective peripheral checkpoints license pathogenic memory B cells in CASPR2-antibody encephalitis.
Sun B, Fernandes D, Soltys J, Kienzler AK, Paneva S, Harrison R, Ramanathan S, Harrison AL, Makuch M, Fichtner ML, Donat RF, Akdeniz D, Bayuangga H, Im MG, Williams R, Vasconcelos A, Thomsen S, Fower A, Sun R, Fox H, Mgbachi V, Davies A, Tseng M, Handel A, Kelly M, Zhao M, Bancroft J, Bashford-Rogers R, Pluvinage JV, Dandekar R, Alvarenga BD, Dustin LB, Rinaldi S, Owens R, Anthony D, Bennett DL, Waters P, Davis SJ, Wilson MR, O'Connor KC, Carvalho AL, Irani SR. Sun B, et al. Sci Adv. 2025 Apr 18;11(16):eadr9986. doi: 10.1126/sciadv.adr9986. Epub 2025 Apr 16. Sci Adv. 2025. PMID: 40238887 Free PMC article.
Permissive central tolerance plus defective peripheral checkpoints licence pathogenic memory B cells in CASPR2-antibody encephalitis.
Sun B, Fernandes D, Kienzler AK, Paneva S, Harrison R, Ramanathan S, Harrison AL, Makuch M, Fichtner ML, Donat RF, Akdeniz D, Bayuangga H, Im MG, Williams R, Vasconcelos A, Thomsen S, Fower A, Sun R, Fox H, Mgbachi V, Davies A, Tseng M, Handel A, Kelly M, Zhao M, Bancroft J, Bashford-Rogers R, Pluvinage JV, Dandekar R, Alvarenga BD, Dustin L, Rinaldi S, Owens R, Anthony D, Bennett DL, Waters P, Davis SJ, Wilson MR, O'Connor KC, Soltys J, Carvalho AL, Irani SR. Sun B, et al. bioRxiv [Preprint]. 2025 Jan 14:2025.01.14.631703. doi: 10.1101/2025.01.14.631703. bioRxiv. 2025. Update in: Sci Adv. 2025 Apr 18;11(16):eadr9986. doi: 10.1126/sciadv.adr9986. PMID: 39868113 Free PMC article. Updated. Preprint.