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Page 1
Showing results for munich cs
Search for Manich CS instead (2 results)
Finding function and form.
Trauner D. Trauner D. Nat Prod Rep. 2014 Apr;31(4):411-3. doi: 10.1039/c4np90008a. Epub 2014 Mar 5. Nat Prod Rep. 2014. PMID: 24595414 No abstract available.
A concise synthesis of tetrodotoxin.
Konrad DB, Rühmann KP, Ando H, Hetzler BE, Strassner N, Houk KN, Matsuura BS, Trauner D. Konrad DB, et al. Science. 2022 Jul 22;377(6604):411-415. doi: 10.1126/science.abn0571. Epub 2022 Jul 21. Science. 2022. PMID: 35862530
Tetrodotoxin (TTX) is a neurotoxic natural product that is an indispensable probe in neuroscience, a biosynthetic and ecological enigma, and a celebrated target of synthetic chemistry. Here, we present a stereoselective synthesis of TTX that proceeds in 22 steps from a glu …
Tetrodotoxin (TTX) is a neurotoxic natural product that is an indispensable probe in neuroscience, a biosynthetic and ecological enigma, and …
Proline-rich antimicrobial peptides targeting protein synthesis.
Graf M, Mardirossian M, Nguyen F, Seefeldt AC, Guichard G, Scocchi M, Innis CA, Wilson DN. Graf M, et al. Nat Prod Rep. 2017 Jul 1;34(7):702-711. doi: 10.1039/c7np00020k. Epub 2017 May 24. Nat Prod Rep. 2017. PMID: 28537612 Free article. Review.
One such subclass is the proline-rich antimicrobial peptides (PrAMPs) that bind to the ribosome and interfere with the process of protein synthesis. A diverse range of PrAMPs have been identified in insects, such as bees, wasps and beetles, and crustaceans, such as crabs, …
One such subclass is the proline-rich antimicrobial peptides (PrAMPs) that bind to the ribosome and interfere with the process of protein …
Structural Elucidation and Antiviral Activity of Covalent Cathepsin L Inhibitors.
Falke S, Lieske J, Herrmann A, Loboda J, Karničar K, Günther S, Reinke PYA, Ewert W, Usenik A, Lindič N, Sekirnik A, Dretnik K, Tsuge H, Turk V, Chapman HN, Hinrichs W, Ebert G, Turk D, Meents A. Falke S, et al. J Med Chem. 2024 May 9;67(9):7048-7067. doi: 10.1021/acs.jmedchem.3c02351. Epub 2024 Apr 17. J Med Chem. 2024. PMID: 38630165 Free PMC article.
Polylactides in additive biomanufacturing.
Poh PSP, Chhaya MP, Wunner FM, De-Juan-Pardo EM, Schilling AF, Schantz JT, van Griensven M, Hutmacher DW. Poh PSP, et al. Adv Drug Deliv Rev. 2016 Dec 15;107:228-246. doi: 10.1016/j.addr.2016.07.006. Epub 2016 Aug 1. Adv Drug Deliv Rev. 2016. PMID: 27492211 Review.
Immunogenicity of Cas9 Protein.
Mehta A, Merkel OM. Mehta A, et al. J Pharm Sci. 2020 Jan;109(1):62-67. doi: 10.1016/j.xphs.2019.10.003. Epub 2019 Oct 4. J Pharm Sci. 2020. PMID: 31589876 Free PMC article.
Click-Shielded and Targeted Lipopolyplexes.
Klein PM, Wagner E. Klein PM, et al. Methods Mol Biol. 2019;2036:141-164. doi: 10.1007/978-1-4939-9670-4_8. Methods Mol Biol. 2019. PMID: 31410795
Both the lipo-oligomer and the DBCO-equipped shielding and targeting agents are produced by solid-phase synthesis (SPS). This enables for precise variation of all functional units, like variation in the amount of DBCO attachment sites or polyethylene glycol (PEG) length. S …
Both the lipo-oligomer and the DBCO-equipped shielding and targeting agents are produced by solid-phase synthesis (SPS). This enables …
Synthetic approaches toward sesterterpenoids.
Hog DT, Webster R, Trauner D. Hog DT, et al. Nat Prod Rep. 2012 Jul;29(7):752-79. doi: 10.1039/c2np20005h. Epub 2012 Jun 1. Nat Prod Rep. 2012. PMID: 22652980 Review.
This review surveys efforts undertaken toward the synthesis of sesterterpenoids, focusing on completed total syntheses and covering ca. 50 natural products in total....
This review surveys efforts undertaken toward the synthesis of sesterterpenoids, focusing on completed total syntheses and covering c …
Synthetic approaches towards alkaloids bearing α-tertiary amines.
Hager A, Vrielink N, Hager D, Lefranc J, Trauner D. Hager A, et al. Nat Prod Rep. 2016 Mar;33(3):491-522. doi: 10.1039/c5np00096c. Epub 2015 Dec 1. Nat Prod Rep. 2016. PMID: 26621771 Review.
A limited number of methods have been described to access this functional group and fewer still are commonly used in synthesis. Herein, we review some approaches to asymmetrically access ATAs and provide an overview of alkaloid total syntheses where those have been employe …
A limited number of methods have been described to access this functional group and fewer still are commonly used in synthesis. Herei …
2,180 results