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Page 1
Association of Combined Anti-Ro52/TRIM21 and Anti-Ro60/SSA Antibodies With Increased Sjögren Disease Severity Through Interferon Pathway Activation.
Bettacchioli E, Saraux A, Tison A, Cornec D, Dueymes M, Foulquier N, Hillion S, Roguedas-Contios AM, Benyoussef AA, Alarcon-Riquelme ME, Pers JO, Devauchelle-Pensec V; PRECISESADS Clinical Consortium, and PRECISESADS Sjögren Consortium. Bettacchioli E, et al. Arthritis Rheumatol. 2024 May;76(5):751-762. doi: 10.1002/art.42789. Epub 2024 Feb 14. Arthritis Rheumatol. 2024. PMID: 38130019
Stratification according to autoantibody status in systemic sclerosis reveals distinct molecular signatures.
Rouvière B, Le Dantec C, Bettacchioli E, Beretta L, Foulquier N, Cao C, Jamin C, Pers JO, Kerick M, Martin J; PRECISESADS Clinical Consortium; PRECISESADS Metabolomic Study Group; Alarcón-Riquelme ME, de Moreuil C, Cornec D, Hillion S. Rouvière B, et al. Ann Rheum Dis. 2024 Oct 22:ard-2024-225925. doi: 10.1136/ard-2024-225925. Online ahead of print. Ann Rheum Dis. 2024. PMID: 39438128 Free article.
Genome-wide association study identifies Sjögren's risk loci with functional implications in immune and glandular cells.
Khatri B, Tessneer KL, Rasmussen A, Aghakhanian F, Reksten TR, Adler A, Alevizos I, Anaya JM, Aqrawi LA, Baecklund E, Brun JG, Bucher SM, Eloranta ML, Engelke F, Forsblad-d'Elia H, Glenn SB, Hammenfors D, Imgenberg-Kreuz J, Jensen JL, Johnsen SJA, Jonsson MV, Kvarnström M, Kelly JA, Li H, Mandl T, Martín J, Nocturne G, Norheim KB, Palm Ø, Skarstein K, Stolarczyk AM, Taylor KE, Teruel M, Theander E, Venuturupalli S, Wallace DJ, Grundahl KM, Hefner KS, Radfar L, Lewis DM, Stone DU, Kaufman CE, Brennan MT, Guthridge JM, James JA, Scofield RH, Gaffney PM, Criswell LA, Jonsson R, Eriksson P, Bowman SJ, Omdal R, Rönnblom L, Warner B, Rischmueller M, Witte T, Farris AD, Mariette X, Alarcon-Riquelme ME; PRECISESADS Clinical Consortium; Shiboski CH; Sjögren’s International Collaborative Clinical Alliance (SICCA); Wahren-Herlenius M, Ng WF; UK Primary Sjögren’s Syndrome Registry; Sivils KL, Adrianto I, Nordmark G, Lessard CJ. Khatri B, et al. Nat Commun. 2022 Jul 27;13(1):4287. doi: 10.1038/s41467-022-30773-y. Nat Commun. 2022. PMID: 35896530 Free PMC article.
Interferon and B-cell Signatures Inform Precision Medicine in Lupus Nephritis.
Parodis I, Lindblom J, Toro-Domínguez D, Beretta L, Borghi MO, Castillo J, Carnero-Montoro E, Enman Y, Mohan C, Alarcón-Riquelme ME, Barturen G, Nikolopoulos D; PRECISESADS Clinical Consortium. Parodis I, et al. Kidney Int Rep. 2024 Mar 13;9(6):1817-1835. doi: 10.1016/j.ekir.2024.03.014. eCollection 2024 Jun. Kidney Int Rep. 2024. PMID: 38899167 Free PMC article.
A new molecular classification to drive precision treatment strategies in primary Sjögren's syndrome.
Soret P, Le Dantec C, Desvaux E, Foulquier N, Chassagnol B, Hubert S, Jamin C, Barturen G, Desachy G, Devauchelle-Pensec V, Boudjeniba C, Cornec D, Saraux A, Jousse-Joulin S, Barbarroja N, Rodríguez-Pintó I, De Langhe E, Beretta L, Chizzolini C, Kovács L, Witte T; PRECISESADS Clinical Consortium; PRECISESADS Flow Cytometry Consortium; Bettacchioli E, Buttgereit A, Makowska Z, Lesche R, Borghi MO, Martin J, Courtade-Gaiani S, Xuereb L, Guedj M, Moingeon P, Alarcón-Riquelme ME, Laigle L, Pers JO. Soret P, et al. Nat Commun. 2021 Jun 10;12(1):3523. doi: 10.1038/s41467-021-23472-7. Nat Commun. 2021. PMID: 34112769 Free PMC article.
Molecular characterisation of lupus low disease activity state (LLDAS) and DORIS remission by whole-blood transcriptome-based pathways in a pan-European systemic lupus erythematosus cohort.
Parodis I, Lindblom J, Barturen G, Ortega-Castro R, Cervera R, Pers JO, Genre F, Hiepe F, Gerosa M, Kovács L, De Langhe E, Piantoni S, Stummvoll G, Vasconcelos C, Vigone B, Witte T; PRECISESADS Clinical Consortium; Alarcón-Riquelme ME, Beretta L. Parodis I, et al. Ann Rheum Dis. 2024 Jun 12;83(7):889-900. doi: 10.1136/ard-2023-224795. Ann Rheum Dis. 2024. PMID: 38373843 Free PMC article.
Novel IgG and IgA autoantibodies validated in two independent cohorts are associated with disease activity and determine organ manifestations in systemic lupus erythematosus: implications for anti-LIN28A, anti-HMGN5, anti-IRF5, and anti-TGIF1.
Lindblom J, Lagutkin D, Sherina N, Idborg H, Beretta L, Borghi MO; PRECISESADS Clinical Consortium; Peyper JM, Barturen G, Jakobsson PJ, Alarcón-Riquelme ME, Nikolopoulos D, Parodis I. Lindblom J, et al. Ann Rheum Dis. 2025 May 9:S0003-4967(25)00896-9. doi: 10.1016/j.ard.2025.04.008. Online ahead of print. Ann Rheum Dis. 2025. PMID: 40348637 Free article.
A Genome-Wide Association Study Suggests New Susceptibility Loci for Primary Antiphospholipid Syndrome.
Casares-Marfil D, Martínez-Bueno M, Borghi MO, Pons-Estel G; PRECISESADS Clinical Consortium; Reales G, Zuo Y, Espinosa G, Radstake T, van den Hoogen LL, Wallace C, Guthridge J, James JA, Cervera R, Meroni PL, Martin J, Knight JS, Alarcón-Riquelme ME, Sawalha AH. Casares-Marfil D, et al. Arthritis Rheumatol. 2024 Nov;76(11):1623-1634. doi: 10.1002/art.42947. Epub 2024 Aug 11. Arthritis Rheumatol. 2024. PMID: 38973605
Variants in the DDX6-CXCR5 autoimmune disease risk locus influence the regulatory network in immune cells and salivary gland.
Wiley MM, Khatri B, Joachims ML, Tessneer KL, Stolarczyk AM, Rasmussen A, Anaya JM, Aqrawi LA, Bae SC, Baecklund E, Björk A, Brun JG, Bucher SM, Dand N, Eloranta ML, Engelke F, Forsblad-d'Elia H, Fugmann C, Glenn SB, Gong C, Gottenberg JE, Hammenfors D, Imgenberg-Kreuz J, Jensen JL, Johnsen SJA, Jonsson MV, Kelly JA, Khanam S, Kim K, Kvarnström M, Mandl T, Martín J, Morris DL, Nocturne G, Norheim KB, Olsson P, Palm Ø, Pers JO, Rhodus NL, Sjöwall C, Skarstein K, Taylor KE, Tombleson P, Thorlacius GE, Venuturupalli S, Vital EM, Wallace DJ, Grundahl KM, Radfar L, Brennan MT, James JA, Scofield RH, Gaffney PM, Criswell LA, Jonsson R, Appel S, Eriksson P, Bowman SJ, Omdal R, Rönnblom L, Warner BM, Rischmueller M, Witte T, Farris AD, Mariette X, Shiboski CH; Sjögren’s International Collaborative Clinical Alliance (SICCA); Wahren-Herlenius M, Alarcón-Riquelme ME; PRECISESADS Clinical Consortium; Ng WF; UK Primary Sjögren’s Syndrome Registry; Sivils KL, Guthridge JM, Adrianto I, Vyse TJ, Tsao BP, Nordmark G, Lessard CJ. Wiley MM, et al. bioRxiv [Preprint]. 2023 Oct 6:2023.10.05.561076. doi: 10.1101/2023.10.05.561076. bioRxiv. 2023. Update in: Ann Rheum Dis. 2025 May 29:S0003-4967(25)00949-5. doi: 10.1016/j.ard.2025.04.023. PMID: 39071447 Free PMC article. Updated. Preprint.
Integration of multi-omics analysis reveals metabolic alterations of B lymphocytes in systemic lupus erythematosus.
Iperi C, Fernández-Ochoa Á, Pers JO, Barturen G, Alarcón-Riquelme M; PRECISESADS Flow Cytometry Study Group, PRECISESADS Clinical Consortium; Quirantes-Piné R, Borrás-Linares I, Segura-Carretero A, Cornec D, Bordron A, Jamin C. Iperi C, et al. Clin Immunol. 2024 Jul;264:110243. doi: 10.1016/j.clim.2024.110243. Epub 2024 May 10. Clin Immunol. 2024. PMID: 38735509 Free article.
35 results