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Tranexamic acid versus placebo in individuals with intracerebral haemorrhage treated within 2 h of symptom onset (STOP-MSU): an international, double-blind, randomised, phase 2 trial.
Yassi N, Zhao H, Churilov L, Wu TY, Ma H, Nguyen HT, Cheung A, Meretoja A, Mai DT, Kleinig T, Jeng JS, Choi PMC, Duc PD, Brown H, Ranta A, Spratt N, Cloud GC, Wang HK, Grimley R, Mahawish K, Cho DY, Shah D, Nguyen TMP, Sharma G, Yogendrakumar V, Yan B, Harrison EL, Devlin M, Cordato D, Martinez-Majander N, Strbian D, Thijs V, Sanders LM, Anderson D, Parsons MW, Campbell BCV, Donnan GA, Davis SM; STOP-MSU Trial Investigators. Yassi N, et al. Lancet Neurol. 2024 Jun;23(6):577-587. doi: 10.1016/S1474-4422(24)00128-5. Epub 2024 Apr 20. Lancet Neurol. 2024. PMID: 38648814 Clinical Trial.
Ultra-Early Hematoma Expansion Is Associated With Ongoing Hematoma Growth and Poor Functional Outcome.
Mutimer CA, Wu TY, Zhao H, Churilov L, Campbell BCV, Cheung A, Meretoja A, Kleinig TJ, Choi PM, Ma H, Cloud GC, Grimley R, Shah D, Ranta A, Mahawish K, Yogendrakumar V, Sharma G, Donnan GA, Davis SM, Yassi N; STOP-MSU Trial Investigators. Mutimer CA, et al. Stroke. 2025 Apr;56(4):838-847. doi: 10.1161/STROKEAHA.124.050131. Epub 2025 Jan 30. Stroke. 2025. PMID: 39882606 Free article. Clinical Trial.